Results 161 to 170 of about 10,301,920 (247)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Original article: adolescent dietary patterns derived using principal component analysis and neuropsychological functions: a cross-sectional analysis of Walnuts Smart Snack cohort. [PDF]

Eur Child Adolesc Psychiatry
Ayala-Aldana N, Pinar-Martí A, Ruiz-Rivera M, Fernández-Barrés S, Romaguera D, Casanova-Mollà J, Solà-Valls N, Julvez J.   +7 more
europepmc   +1 more source

Original Article--Surgical site infections following pediatric cardiac surgery in a tertiary care hospital: Rate and risk factors. [PDF]

J Saudi Heart Assoc, 2021
Alshaya MA, Almutairi NS, Shaath GA, Aldosari RA, Alnami SK, Althubaiti A, Abu-Sulaiman RM.   +6 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Response by the Authors of Original Article. [PDF]

J Neurol Surg B Skull Base, 2019
Fnais N, Di Maio S, Edionwe S, Zeitouni A, Sirhan D, Valdes CJ, Tewfik MA.   +6 more
europepmc   +2 more sources

Original Article--Risk Factors for Neurological Complications and Short-term Outcomes After Pediatric Heart Surgery: A Retrospective Analysis. [PDF]

J Saudi Heart Assoc
Shahzad M, Alheraish YA, Algethami B, Algheryafi LA, Kamel S, Ghunaim R, Alhalees ZY.   +6 more
europepmc   +1 more source

Author's reply to the Letter to the Editor on the original article "Lack of changes in preterm delivery and stillbirths during COVID-19 lockdown in a European region" by Juan Arnaez. [PDF]

Eur J Pediatr, 2021
Arnaez J, Ochoa-Sangrador C, Garcia-Alix A.   +2 more
europepmc   +1 more source

Correction to “Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability”

Molecular Oncology, EarlyView.
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source