Results 141 to 150 of about 2,704,487 (327)

Aquinas at 800 – Papers from the 2024 Notre Dame Conference: Human Nature and Original Sin in Thomas Aquinas [PDF]

Harm Goris
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Hexamerization: explaining the original sin of IgG-mediated complement activation in acute lung injury. [PDF]

J Clin Invest
Kulkarni HS.
europepmc   +1 more source

Diversification, Original Sin, and International Bond Portfolios

, 2003
John D. Burger, Francis E. Warnock
openalex   +1 more source

Grégor Puppinck, Mi deseo es la ley. Los derechos del hombre sin naturaleza, Trad. F. Montesinos y M. Montes, Ediciones Encuentro, Madrid, 2020, 288 pp. (Edición original en francés 2018)

, 2021
C.I. Massini-Correas
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Rethinking the Debates on the Theological Implications of the Biological Theory of Human Evolution on the Creation of Adam

African Theological Journal for Church and Society
The subject of the creation of Adam raises a seeming contention between Christian evolutionists and Christian antievolutionists, and this is evident in many ways including in the Scopes Trial of 1925 in Tennessee, USA.
Stephen Hosea Vongdip, Kingsley Nelson Kinya, Jock Matthew Agai   +2 more
doaj  

Good-Bye Original Sin, Hello Risk On-Off, Financial Fragility, and Crises? [PDF]

, 2020
J. Aizenman, Yothin Jinjarak, Donghyun Park, Huanhuan Zheng   +3 more
semanticscholar   +1 more source