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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A Physical Model for Regulation-First in the Proto-Liver Origin of Life (PLOL) Framework
van der Merwe, Emile S.
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Angewandte Chemie International Edition in English, 1973
AbstractThe theory of the evolution of the species, which is today widely accepted, requires a starting point. It is postulated that the biological starting point could have emerged only if chemical evolution had preceded it. Experiments are described which show the formation of organic substances from inorganic gases under conditions which prevailed ...
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AbstractThe theory of the evolution of the species, which is today widely accepted, requires a starting point. It is postulated that the biological starting point could have emerged only if chemical evolution had preceded it. Experiments are described which show the formation of organic substances from inorganic gases under conditions which prevailed ...
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1998
Abstract Every religion has an account of the origins of life. Most familiar to Western traditions is Genesis 1, a spare, poetic account of the six days of creation. The Pueblo Indians tell of a primordial home beneath a lake where humans, gods, and animals lived together while the earth above was still soft and “unripe.” The Kagaba ...
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Abstract Every religion has an account of the origins of life. Most familiar to Western traditions is Genesis 1, a spare, poetic account of the six days of creation. The Pueblo Indians tell of a primordial home beneath a lake where humans, gods, and animals lived together while the earth above was still soft and “unripe.” The Kagaba ...
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
2009
Previous Entry iconEncyclopedia Next Entry The origin of life remains today one of the most challenging puzzles to science. The challenge is twofold: (1) qualify the essence of life and (2) explain its appearance on Earth. Although both aspects have been subject to much scientific investigation, no satisfactory explanation has been formulated so far.
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Previous Entry iconEncyclopedia Next Entry The origin of life remains today one of the most challenging puzzles to science. The challenge is twofold: (1) qualify the essence of life and (2) explain its appearance on Earth. Although both aspects have been subject to much scientific investigation, no satisfactory explanation has been formulated so far.
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Abstract All living beings use the same genetic code; hence they derive from a common ancestor. Carbonaceous meteorites and comets contain organic matter, whose carbon isotopic signature points to an abiotic origin. However, these extraterrestrial precursor molecules of life never reach the complexity of the large molecules of living ...
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