Results 101 to 110 of about 2,974 (211)

IWGDF/IDSA guidelines on the diagnosis and treatment of diabetes‐related foot infections (IWGDF/IDSA 2023)

open access: yesDiabetes/Metabolism Research and Reviews, Volume 40, Issue 3, March 2024.
Abstract The International Working Group on the Diabetic Foot (IWGDF) has published evidence‐based guidelines on the management and prevention of diabetes‐related foot diseases since 1999. The present guideline is an update of the 2019 IWGDF guideline on the diagnosis and management of foot infections in persons with diabetes mellitus.
Éric Senneville   +13 more
wiley   +1 more source

Drug delivery systems for potential treatment of intracellular bacterial infections. [PDF]

open access: yes, 2010
Despite the advent of a considerable number of new antibiotics, treatment of intracellular pathogens still represents a major pharmaceutical challenge.
Ariza, J. (J.)   +3 more
core   +1 more source

Interventions in the management of diabetes‐related foot infections: A systematic review

open access: yesDiabetes/Metabolism Research and Reviews, Volume 40, Issue 3, March 2024.
Abstract The optimal approaches to managing diabetic foot infections remain a challenge for clinicians. Despite an exponential rise in publications investigating different treatment strategies, the various agents studied generally produce comparable results, and high‐quality data are scarce. In this systematic review, we searched the medical literature
Edgar J. G. Peters   +13 more
wiley   +1 more source

Cyclic Peptides for Drug Development

open access: yesAngewandte Chemie, Volume 136, Issue 3, January 15, 2024.
Cyclic peptides combine a number of favorable properties that make them attractive for drug development. Today, more than 40 therapeutics based on cyclic peptides are in use, and new, powerful technologies for their development suggest that this number could grow rapidly.
Xinjian Ji   +2 more
wiley   +1 more source

Kimyrsa and Orbactiv – A Tale of Two Formulations

open access: yesDrug Design, Development and Therapy, 2023
Brittany T Jackson,1 David B Cluck,2 Andrés F Henao-Martínez,3 Daniel B Chastain4 1Department of Pharmacy, Mount Sinai Morningside, New York, NY, 10025, USA; 2Department of Pharmacy Practice, Bill Gatton College of Pharmacy East Tennessee State ...
Jackson BT   +3 more
doaj  

VanZ Reduces the Binding of Lipoglycopeptide Antibiotics to Staphylococcus aureus and Streptococcus pneumoniae Cells

open access: yesFrontiers in Microbiology, 2020
vanZ, a member of the VanA glycopeptide resistance gene cluster, confers resistance to lipoglycopeptide antibiotics independent of cell wall precursor modification by the vanHAX genes.
Vladimir Vimberg   +4 more
doaj   +1 more source

Programming stress-induced altruistic death in engineered bacteria. [PDF]

open access: yes, 2012
Programmed death is often associated with a bacterial stress response. This behavior appears paradoxical, as it offers no benefit to the individual. This paradox can be explained if the death is 'altruistic': the killing of some cells can benefit the ...
Buchler, NE, Pai, A, Tanouchi, Y, You, L
core   +1 more source

A few atoms make the difference: Synthetic, CD, NMR and computational studies on antiviral and antibacterial activities of glycopeptide antibiotic aglycon derivatives [PDF]

open access: yes, 2018
K
Batta, Gyula   +14 more
core   +1 more source

Templated deprotonative metalation of polyaryl systems : facile access to simple, previously inaccessible multi-iodoarenes [PDF]

open access: yes, 2017
The development of new methodologies to affect non-ortho functionalization of arenes has emerged as a globally important arena for research, which is key to both fundamental studies and applied technologies.
Fleming, Ben J.   +5 more
core   +1 more source

Profile of oritavancin and its potential in the treatment of acute bacterial skin structure infections

open access: yesInfection and Drug Resistance, 2015
Subhashis Mitra, Usman Saeed, Daniel H Havlichek, Gary E Stein Department of Infectious Diseases, Michigan State University, East Lansing, MI, USA Abstract: Oritavancin, a semisynthetic derivative of the glycopeptide antibiotic chloroeremomycin ...
Mitra S, Saeed U, Havlichek DH, Stein GE
doaj  

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