Results 1 to 10 of about 263,111 (199)

Research Communication: Real-World Effectiveness of Budesonide Orodispersible Tablets for Eosinophilic Oesophagitis: The Importance of Patience and Education. [PDF]

Aliment Pharmacol Ther
Budesonide orodispersible tablets (BOT) have been shown to be efficacious for eosinophilic oesophagitis (EoE) in clinical trials. This study evaluated the real‐world effectiveness of BOT in a retrospective cohort of 94 patients across six tertiary ...
Taylor S, Barwick E, Perananthan V, Parkash N, Lucas S, Chauhan A, Yu C, Tan K, Sepe G, Suleiman M, Lewis D, Basnayake C, Philpott H, Nandurkar S, Burgell R, Garg M.   +15 more
europepmc   +3 more sources

Preparation of orodispersible tablets of bosentan using xylitol and menthol as dissolution enhancers [PDF]

Scientific Reports
Bosentan is a drug used to treat pulmonary hypertension via dual endothelial receptor antagonism. Bosentan has a restricted oral bioavailability, a problem that's mostly due to poor solubility and hepatic metabolism.
Rania Mohamed Sakr, Abdelaziz El Sayed Abdelaziz, Eman Ahmed Mazyed, Gamal Mohamed El Maghraby   +3 more
doaj   +3 more sources

Development of Orodispersible Tablets with Solid Dispersions of Fenofibrate and Co-Processed Mesoporous Silica for Improved Dissolution [PDF]

Pharmaceutics
Poor water solubility is an important challenge in the development of oral patient-friendly solid dosage forms. This study aimed to prepare orodispersible tablets with solid dispersions of a poorly water-soluble drug fenofibrate and a co-processed ...
Ana Baumgartner, Odon Planinšek
doaj   +3 more sources

Pharmacotechnical and analytical preformulation studies for cannabidiol orodispersible tablets [PDF]

Saudi Pharmaceutical Journal, 2021
Obtaining orodispersible tablets (ODT) containing substances from the second Biopharmaceutical Class has raised concerns as the dissolution test is challenging.
Robert-Alexandru Vlad, Paula Antonoaea, Nicoleta Todoran, Daniela-Lucia Muntean, Emőke Margit Rédai, Oana Alexandra Silași, Anamaria Tătaru, Magdalena Bîrsan, Silvia Imre, Adriana Ciurba   +9 more
doaj   +4 more sources

Oesophageal Lichen Planus Successfully Treated with Budesonide Orodispersible Tablets: A Case Report [PDF]

Case Reports in Gastroenterology
Introduction: Lichen planus is a relatively common inflammatory condition of the nails, skin, and mucosal surfaces. Oesophageal involvement of lichen planus is thought to be very rare, mainly described in case reports, but is associated with a high risk ...
Harald Bagger-Jörgensen, Mohammed Abdulrasak, Kevin Sandeman, Mohammed Binsalman, Klas Sjöberg   +4 more
doaj   +3 more sources

A retrospective real-world study on the safety and efficacy of budesonide orodispersible tablets for the induction therapy of eosinophilic oesophagitis [PDF]

Therapeutic Advances in Gastroenterology
Background: An orodispersible form of budesonide has recently been approved for the targeted treatment of eosinophilic oesophagitis in the United Kingdom, Europe, Australia, Canada and the United States, following favourable results from a randomised ...
Rachel Geow, Gina Arena, Chiang Siah, Sherman Picardo   +3 more
doaj   +3 more sources

Formulation and Evaluation of Polymeric Spherical Agglomerates-Based Porous Orodispersible Tablets of Cilnidipine. [PDF]

Pharmaceutics
Background/Objectives: Cilnidipine (CIL) is a calcium channel blocker that exhibits low bioavailability (~13%) due to poor aqueous solubility and extensive pre-systemic gut wall metabolism.
Alhamhoom Y, Prakash SS, Kumar A, Nanjappa SH, Rahamathulla M, Kamath MS, Farhana SA, Ahmed MM, Boreddy-Shivanandappa T.   +8 more
europepmc   +2 more sources

Characterization of orodispersible tablets and orodispersible films [PDF]

Arhiv za farmaciju, 2018
Orodispersible dosage forms are intended to be placed on tongue where, in contact with limited saliva volume, fast disintegration, followed by facilitated swallowing, occurred. Intraoral disintegration might be accompanied by drug release and dissolution
Drašković Milica, Cvijić Sandra, Ibrić Svetlana, Parojčić Jelena   +3 more
doaj   +3 more sources

Study on Lyophilised Orodispersible Tablets from Plant-Based Drinks as Bulking Agents. [PDF]

Pharmaceutics
Background/Objectives: Oral administration of active pharmaceutical ingredients (APIs) is the most commonly used route of administration. As dysphagia is a prevalent problem, the size of the swallowed dosage form could negatively influence patient ...
Demeter AK, Farkas D, Király M, Kovács Z, Ludányi K, Antal I, Kállai-Szabó N.   +6 more
europepmc   +2 more sources

Quality by Design Formulation Approach for the Development of Orodispersible Tablets of Dexlansoprazole. [PDF]

Drug Des Devel Ther
Purpose Dexlansoprazole (DX) is a commercially available proton pump inhibitor (PPI). It is an oral delayed-release (DR) formulation that takes 1–2 h to reach the systemic circulation.
Ali AT, Nasir F, Hidayatullah T, Pervez S, Rabqa Zainab S, Gohar S, Ur Rahman A, Khattak MA, Alasmari F, Neau SH, Maryam GE.   +10 more
europepmc   +2 more sources