Results 11 to 20 of about 263,111 (199)

Choosing the "Ideal" Oral Dosage Form for Pediatric Patients: Parents' Perspectives on Children's Preferences with a Focus on Orodispersible Tablets. [PDF]

Children (Basel)
Background: Developing suitable dosage forms presents multiple challenges, such as ensuring the medication can be easily swallowed by young children, mixed with a small amount of food or liquid, and effectively taste-masked.
Gvozdeva Y, Staynova R.
europepmc   +2 more sources

In Vitro/In Vivo Evaluation of Clomipramine Orodispersible Tablets for the Treatment of Depression and Obsessive-Compulsive Disorder. [PDF]

Pharmaceuticals (Basel), 2023
The first and only antidepressant drug on the market with solid proof of clinically significant serotonin and noradrenaline reuptake inhibition is clomipramine (CLP). However, significant first-pass metabolism reduces its absorption to less than 62%.
Ghumman SA, Hameed H, Noreen S, Al-Hussain SA, Kausar R, Irfan A, Shabbir R, Rana M, Amanat A, Zaki MEA.   +9 more
europepmc   +2 more sources

Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets [PDF]

Pharmaceuticals, 2022
The novelty in this study is the development of new orodispersible tablets containing nifedipine (NIF) as the active ingredient. Initially, the formation of inclusion complexes between nifedipine and two derivatives of beta-cyclodextrin, namely ...
Emma Adriana Ozon, Marian Novac, Daniela Gheorghe, Adina Magdalena Musuc, Mirela Adriana Mitu, Iulian Sarbu, Valentina Anuta, Adriana Rusu, Simona Petrescu, Irina Atkinson, Dumitru Lupuliasa   +10 more
doaj   +2 more sources

Formulation and Evaluation of pH-Modulated Amorphous Solid Dispersion-Based Orodispersible Tablets of Cefdinir. [PDF]

Pharmaceutics
Cefdinir (CEF) is a semi-synthetic third-generation broad-spectrum oral cephalosporin that exhibits poor solubility at lower pH values. Considering this, pH-modulated CEF solid dispersions (ASDs) were produced by solvent evaporation method employing ...
Alhamhoom Y, Kumaraswamy T, Kumar A, Nanjappa SH, Prakash SS, Rahamathulla M, Thajudeen KY, Ahmed MM, Shivanandappa TB.   +8 more
europepmc   +2 more sources

Sugar content and erosive potential of commonly prescribed Orodispersible tablets- An in vitro study. [PDF]

F1000Res, 2023
Background: Dental caries is a major non-communicable disease of public health concern caused due to freely available dietary sugars. We aimed to compare the sugar content and erosive potential with duration of use and drug classes of orodispersible ...
Anand L, Pentapati K, Shenoy R, Yelleti G, Kumar S.   +4 more
europepmc   +2 more sources

Fabrication and Assessment of Orodispersible Tablets Loaded with Cubosomes for the Improved Anticancer Activity of Simvastatin against the MDA-MB-231 Breast Cancer Cell Line. [PDF]

Polymers (Basel), 2023
Various factors limit the use of simvastatin as an anticancer drug. Therefore, this study aimed to analyse simvastatin (SIM)-loaded cubosome efficacy against breast cancer.
Zaki RM, El Sayeh Abou El Ela A, Almurshedi AS, Aldosari BN, Aldossari AA, Ibrahim MA.   +5 more
europepmc   +2 more sources

The popularization of orodispersible tablets in the pharmaceutical market [PDF]

Infarma: Pharmaceutical Sciences, 2018
Orodispersible tablets are getting popular due to its easy administration which leads to a higher therapeutic adherence. This study aimed to evaluate the state of the art of these drug products based on the scientific literature.
Ludmila Alvim PINHO, Ana Claudia TEMER, Caroline RIBEIRO, Livia Lira SÁ-BARRETO, Marcilio Sergio Soares CUNHA-FILHO   +4 more
doaj   +2 more sources

Bioequivalence and Safety of Bilastine 20 mg Orodispersible Tablets and Conventional Tablets: A Randomized, Single-Dose, Two-Period Crossover Study in Healthy Volunteers Under Fasting Conditions. [PDF]

Drugs R D
Orodispersible tablets (ODT) rapidly dissolve in the oral cavity and can improve patient’s convenience. This pharmacokinetic study assessed the bioequivalence of a novel 20 mg ODT formulation of bilastine compared with bilastine 20 mg tablets in healthy ...
Román M, Ochoa D, Martin S, Luquero S, Gilaberte I, Arranz P, Sánchez C.   +6 more
europepmc   +2 more sources

Fused Deposition Modeling as a Possible Approach for the Preparation of Orodispersible Tablets [PDF]

Pharmaceuticals, 2022
Additive manufacturing technologies are considered as a potential way to support individualized pharmacotherapy due to the possibility of the production of small batches of customized tablets characterized by complex structures.
Thao Tranová, Jolanta Pyteraf, Mateusz Kurek, Witold Jamróz, Witold Brniak, Dita Spálovská, Jan Loskot, Karolina Jurkiewicz, Joanna Grelska, Daniel Kramarczyk, Jitka Mužíková, Marian Paluch, Renata Jachowicz   +12 more
doaj   +2 more sources

Formulation and In Vitro Evaluation of Taste- Masked Prednisolone Orodispersible Tablets

مجلة كلية الطب, 2023
Background: prednisolone is a corticosteroid with a very bitter taste acts as anti- anti-inflammatory and immune suppressant drug and it is used at any age.
Hiba mohammed Suza ali, Eman B. H. Al-Khedairy   +1 more
doaj   +2 more sources