Formulation and development of paediatric orally disintegrating carbamazepine tablets
Carbamazepine is a medicine used to manage epilepsy and partial or tonic-clonic seizures. This study aimed at formulating and obtaining carbamazepine orodispersible tablets for paediatric use at a 50 mg dose, with a diameter not greater than 6 mm and a ...
R Canadell-Heredia +5 more
doaj +1 more source
The effects of croscarmellose sodium concentration on the physicochemical characteristics of orodispersible tablets of atenolol [PDF]
Hypertension is the most common cardiovascular diseases suffered by geriatric patients. Their physiological changes make the administration of conventional tablets less effective, especially regarding compliance.
Nani Parfati, Karina Citra Rani
doaj +1 more source
Ebastine is a long-acting, nonsedating, second-generation antihistaminic drug that prevents histamine action, mainly in immediate hypersensitivity.
Bhawana Dhakal +8 more
doaj +1 more source
The main objective of this study consists in establishing the influence of the intergranular superdisintegrant on the specific properties of drotaverine hydrochloride fast-dissolving granules (DROT-FDGs) and orodispersible tablets (DROT-ODTs).
Robert-Alexandru Vlad +7 more
doaj +1 more source
Orodispersible Tablets: A Compendious Review
In recent times, there has been an enhanced demand for more patient compliant dosage forms. Oral route has been the gold standard in the administration of medications due to its safety, good patient compliance, ease of ingestion, pain avoidance and versatility. Dysphagia poses a problem especially in geriatric and paediatric patients. Mentally retarded
H.S Keerthy, Kenneth Roshan
openaire +1 more source
Formulation of orodispersible atenolol-β-cyclodextrin tablets with co-processed crospovidone-croscarmellose sodium and poloxamer 188 [PDF]
The use of conventional tablets in geriatric patients is currently limited because of a decrease in their physiological functions, such as tremor and difficulty of swallowing pills, which lowers their compliance with drug therapy.
Karina Citra Rani +3 more
doaj +1 more source
Formulation and characterization of orodispersible tablet of glimepiride
The present study is regarding, Glimepiride is one derivatives of sulfonyl urea used in the treatment of Type II DM which classified as class-II (BCS) of high permeability and low degree of solubility. The endeavor is to improve its solubility by solvent vaporization method to enhance the rate of dissolution of glimepiride ...
Ahmad AB Yosef Kinani +1 more
openaire +3 more sources
Pharmaceutical Cocrystal of Piroxicam: Design, Formulation and Evaluation [PDF]
Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid sate properties of drug substances like solubility and dissolution.
Prabhakar Panzade +3 more
doaj +1 more source
High-Shear Wet Granulation of SMEDDS Based on Mesoporous Carriers for Improved Carvedilol Solubility
Mesoporous carriers are a convenient choice for the solidification of self-microemulsifying drug delivery systems (SMEDDS) designed to improve the solubility of poorly water-soluble drugs.
Mila Kovačević +3 more
doaj +1 more source
Cost-utility analysis of sequential therapies for pediatric-onset eosinophilic esophagitis. [PDF]
Abstract Objectives Topical corticosteroids, proton‐pump inhibitors (PPI) and elimination diets (ED) are equally recommended as first‐line therapies for pediatric eosinophilic esophagitis (EoE). Dupilumab (DUP) is usually used for refractoriness. We aim to assess the cost‐utility of all potential sequential treatments for EoE.
Arcos-Machancoses JV +2 more
europepmc +2 more sources

