Results 51 to 60 of about 263,111 (199)

Orodispersible films and tablets with prednisolone microparticles

open access: yesEuropean Journal of Pharmaceutical Sciences, 2015
Orodispersible tablets (ODTs) and orodispersible films (ODFs) are solid oral dosage forms disintegrating or dissolving rapidly when placed in the mouth. One of the main issues related to their preparation is an efficient taste masking of a bitter drug substance. Therefore, the aim of this study was to prepare and evaluate the microparticles intended to
Brniak, Witold   +2 more
openaire   +3 more sources

Development and characterization of solid dispersion-based orodispersible tablets of cilnidipine

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2022
Background Cilnidipine, a calcium channel blocker, is the first-line drug for hypertension and belongs to Biopharmaceutics Classification System II. To mitigate its extensive first-pass metabolism and improve patient compliance, the present study was ...
Murugesan Mohana   +1 more
doaj   +1 more source

Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for Paediatric Use

open access: yesPharmaceutics, 2023
One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and hence clinical outcomes.
Jiayu Hu   +3 more
doaj   +1 more source

Formulation and Optimization of Zolmitriptan Orodispersible Tablets

open access: yesJournal of Drug Delivery and Therapeutics, 2021
Zolmitriptan is a selective 5-hydroxytryptamine receptor agonist reported for the acute migraine treatment, having poor water solubility leads to poor bioavailability. In the present study, attempt to improve the bioavailability of zolmitriptan with the help of PVP K-30 using the microwave irradiation method.
N. Rama Rao   +3 more
openaire   +2 more sources

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

open access: yesPediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics   +16 more
wiley   +1 more source

DEVELOPMENT OF ORODISPERSIBLE TABLETS OF LORATADINE CONTAINING AN AMORPHOUS SOLID DISPERSION OF THE DRUG IN SOLUPLUS® USING DESIGN OF EXPERIMENTS

open access: yesInternational Journal of Pharmacy and Pharmaceutical Sciences, 2023
Objective: The objective of the present work was to develop an orodispersible tablet of loratadine, an orally active, non-sedating anti-histaminic, belonging to BCS Class II.
H. Nair   +2 more
semanticscholar   +1 more source

Effect of Budesonide Oral Suspension on Time to First Dysphagia Symptom Response and Dysphagia Symptom Resolution Outcomes in Patients With Eosinophilic Esophagitis

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 927-936, March 2026.
ABSTRACT Background and Aim We examined post hoc the effect of budesonide oral suspension (BOS/Eohilia) 2.0 mg twice daily (b.i.d.) on dysphagia symptom outcomes in patients with eosinophilic esophagitis (EoE). Methods Patients aged 11–55 years who received BOS 2.0 mg b.i.d.
Evan S. Dellon   +7 more
wiley   +1 more source

Psyllium (Plantago Ovata Forsk) Husk Powder as a Natural Superdisintegrant for Orodispersible Formulations: A Study on Meloxicam Tablets

open access: yesMolecules, 2019
(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2)
Gailute Draksiene   +3 more
doaj   +1 more source

Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 1, Page 60-69, January 2026.
Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz   +11 more
wiley   +1 more source

Development and evaluation of or dispersible tablet of Propranolol Hydrochloride by sublimation technique

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2013
Propranolol Hydrochloride (PHCl) is a synthetic beta adrenergic receptor blocking agent used widely in the treatment of angina pectoris, cardiac arrhythmias and hypertension.
Mowafaq M. G.
doaj   +1 more source

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