Results 51 to 60 of about 263,111 (199)
Orodispersible films and tablets with prednisolone microparticles
Orodispersible tablets (ODTs) and orodispersible films (ODFs) are solid oral dosage forms disintegrating or dissolving rapidly when placed in the mouth. One of the main issues related to their preparation is an efficient taste masking of a bitter drug substance. Therefore, the aim of this study was to prepare and evaluate the microparticles intended to
Brniak, Witold +2 more
openaire +3 more sources
Development and characterization of solid dispersion-based orodispersible tablets of cilnidipine
Background Cilnidipine, a calcium channel blocker, is the first-line drug for hypertension and belongs to Biopharmaceutics Classification System II. To mitigate its extensive first-pass metabolism and improve patient compliance, the present study was ...
Murugesan Mohana +1 more
doaj +1 more source
One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and hence clinical outcomes.
Jiayu Hu +3 more
doaj +1 more source
Formulation and Optimization of Zolmitriptan Orodispersible Tablets
Zolmitriptan is a selective 5-hydroxytryptamine receptor agonist reported for the acute migraine treatment, having poor water solubility leads to poor bioavailability. In the present study, attempt to improve the bioavailability of zolmitriptan with the help of PVP K-30 using the microwave irradiation method.
N. Rama Rao +3 more
openaire +2 more sources
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics +16 more
wiley +1 more source
Objective: The objective of the present work was to develop an orodispersible tablet of loratadine, an orally active, non-sedating anti-histaminic, belonging to BCS Class II.
H. Nair +2 more
semanticscholar +1 more source
ABSTRACT Background and Aim We examined post hoc the effect of budesonide oral suspension (BOS/Eohilia) 2.0 mg twice daily (b.i.d.) on dysphagia symptom outcomes in patients with eosinophilic esophagitis (EoE). Methods Patients aged 11–55 years who received BOS 2.0 mg b.i.d.
Evan S. Dellon +7 more
wiley +1 more source
(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2)
Gailute Draksiene +3 more
doaj +1 more source
Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders
Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz +11 more
wiley +1 more source
Propranolol Hydrochloride (PHCl) is a synthetic beta adrenergic receptor blocking agent used widely in the treatment of angina pectoris, cardiac arrhythmias and hypertension.
Mowafaq M. G.
doaj +1 more source

