Results 21 to 30 of about 1,031,753 (244)

Influence of sleep quality on pain characteristics, anxiety symptoms and catastrophizing in patients with painful temporomandibular disorders treated in private orofacial pain clinic

open access: yesBrJP
BACKGROUND AND OBJECTIVES: Extensive literature has shown that poor sleep quality, anxiety symptoms and catastrophizing contribute to worsening of temporomandibular disorder (TMD) conditions.
Claudia Aparecida de Oliveira Machado   +3 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Effect on orofacial pain in patients with chronic pain participating in a multimodal rehabilitation programme – a pilot study

open access: yes, 2023
OBJECTIVES: Orofacial pain in patients taking part in a multimodal rehabilitation programme (MMRP) due to chronic bodily pain is common but it is not known whether such a rehabilitation programme can also have an effect on the presence of orofacial pain.
Simon Vallin   +9 more
core   +1 more source

Limited Mouth Opening Secondary to Diffuse Systemic Sclerosis

open access: yesCase Reports in Dentistry, 2013
Systemic sclerosis (SSc) is a relatively rare condition with an immunologically mediated pathogenesis. For reasons that are not clearly understood, dense collagen is deposited in the connective tissues of the body in extraordinary amounts.
Tomoko Wada, Saravanan Ram
doaj   +1 more source

A Rare Case of Idiopathic Painful Nervus Intermedius Neuropathy in a 13-Year-Old Female: A Case Report and Discussion in the Context of the Literature

open access: yesChildren, 2022
(1) Background: Painful nervus intermedius neuropathy involves continuous or near-continuous pain affecting the distribution of the intermedius nerve(s). The diagnosis of this entity is challenging, particularly when the clinical and demographic features
Diego Fernandez-Vial   +2 more
doaj   +1 more source

Single‐cell RNA sequencing of peripheral blood defines two immunological subtypes of Sjögren's disease distinguished by anti‐SSA antibodies and aberrant B cell populations

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Sjögren's disease (SjD) is a heterogeneous autoimmune disorder characterized by substantial clinical and molecular diversity. This heterogeneity raises key questions regarding the existence of distinct pathogenic mechanisms underlying disease subtypes.
Geoffrey Urbanski   +15 more
wiley   +1 more source

Profession‐Related Accreditation Requirements in Australia Regarding Anatomy Teaching: A Web‐Based Desktop Audit

open access: yesClinical Anatomy, EarlyView.
ABSTRACT For effective and safe practice, health professionals need an understanding of functional anatomy. Registration boards, councils or self‐regulating professional associations determine the standards, codes, graduate competencies and education program accreditation requirements which inform health curricula development and content.
Anita Zacharias   +5 more
wiley   +1 more source

Akt2 inhibition alleviates temporomandibular joint osteoarthritis by preventing subchondral bone loss

open access: yesArthritis Research & Therapy
Background This study aimed to investigate the role and mechanism of the Akt2 pathway in different stages of anterior disc displacement (ADD)-induced temporomandibular joint osteoarthritis (TMJOA).
Shi-Yang Feng   +5 more
doaj   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

open access: yesEpileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron   +6 more
wiley   +1 more source

Recommendations by the EACD for examination, diagnosis, and management of patients with temporomandibular disorders and orofacial pain by the general dental practitioner

open access: yes, 2008
The Council fo the European Academy of Craniomandibular Disorders charged the Educational Committee with the task of establishing Guidelines and Recommendations for the examination, diagnosis, and management of patients with temporomandibular disorders ...
de Boever, Jan A   +3 more
core   +2 more sources

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