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Pain relief by supraspinal gabapentin requires descending noradrenergic inhibitory controls [PDF]
PAIN Reports, 2018 . Introduction:. Gabapentin regulates pain processing by direct action on primary afferent nociceptors and dorsal horn nociresponsive neurons. Through an action at supraspinal levels, gabapentin also engages descending noradrenergic inhibitory controls ...
Dina L. Juarez-Salinas +3 more
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Perbedaan Efektivitas Gabapentin, Deksametason, dan Gabapentin+Deksametason terhadap Angka Kejadian PONV Pascaoperasi Telinga Tengah [PDF]
Jurnal Anestesi Perioperatif, 2022 Post operative nausea vomiting (PONV) merupakan salah satu komplikasi tersering pascaoperatif terutama pada operasi risiko tinggi seperti operasi telinga tengah.
Sugeng Budi Santosa +2 more
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Thai Journal of Obstetrics and Gynaecology, 2021 Objectives: To evaluate the effect of gabapentin 300 mg in relieving acute postoperative pain in patients undergoing total abdominal hysterectomy at Chonburi Hospital. Materials and Methods: A double-blind, randomized, controlled
Hathaipat Sukjariangporn +1 more
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Journal of Pharmaceutical Policy and PracticeBackground: Gabapentin is increasingly recognised for its potential for abuse, raising concerns within healthcare communities. Community pharmacists are on the front lines in identifying and addressing instances of gabapentin abuse, making their insights
Rana Abu-Farha +7 more
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Endogenous GABA Does Not Mediate the Inhibitory Effects of Gabapentin on Spinal Reflexes in Rats
Journal of Pharmacological Sciences, 2004 The novel antiepileptic drug gabapentin was designed as a structural analog of γ-aminobutyric acid (GABA). However, its mechanism of action remains unclear. In the present study, we investigated the effect of gabapentin on spinal reflexes in anesthetized
Shinobu Shimizu +4 more
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Journal of Pain Research, 2023 Jufriady Ismy,1 Dessy R Emril,2 Said Alfin Khalilullah,1 Muhammad Puteh Mauny1 1Department of Urology, Faculty of Medicine, Universitas Syiah Kuala/Dr.
Ismy J +3 more
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eJHaem, 2021 Pain in sickle cell disease (SCD) can have a neuropathic component. This randomized phase II double‐blinded placebo‐controlled study evaluated the efficacy of gabapentin in reducing pain and opioid consumption (morphine‐equivalent dose [MED]) during ...
Latika Puri +7 more
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GABAB Receptors Do Not Mediate the Inhibitory Actions of Gabapentin on the Spinal Reflex in Rats
Journal of Pharmacological Sciences, 2004 The clinical effectiveness of gabapentin for the treatment of epilepsy, spasticity, and neuropathic pain has been established. The mechanisms responsible for those actions, however, are still not clearly understood.
Shinobu Shimizu +3 more
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Efficacy Of Gabapentin In Trigeminal Neuralgia: A Non-randomized Trial
Journal of Bahria University Medical and Dental College, 2021 Objective: To compare the efficacy of Gabapentin with carbamazepine in Trigeminal Neuralgia. Material/Method: The study was conducted in Agha Khan University Hospital and Abbasi Shaheed Hospital for four months.
Nasir Ali Khan +6 more
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Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin
Brazilian Journal of Nephrology, 2012 INTRODUCTION: Uremic pruritus is common among dialysis patients. Effective treatments are not readily available. Early evidence with antihistamines and gabapentin indicate variable effects.
Diego Marquez +9 more
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