Results 1 to 10 of about 27,995 (239)

Pregabalin for the management of fibromyalgia syndrome

Journal of Pain Research, 2010
Chad S BoomershineDepartment of Medicine, Vanderbilt University, Nashville, TN, USAAbstract: This last article in a three-part series on approved medications for managing fibromyalgia syndrome (FMS) reviews pregabalin (Lyrica®).
Chad S Boomershine
doaj   +1 more source

Melatonin versus pregabalin as oral premedication in adult patients undergoing lower-extremity amputation under spinal anesthesia [PDF]

Al-Azhar International Medical Journal
Objectives: To assess how well pregabalin and melatonin work as premedication to reduce perioperative anxiety and post-surgical discomfort in individuals having lower limb amputations while given spinal anesthesia.Methods: Participants were split up into
Amira Awad, Amira Lashin, Zeinab Ibrahim, Fatma Alzahraa Elkemary   +3 more
doaj   +1 more source

The Need to Include Pregabalin in Routine Substance Screening Panels to Detect Non-Therapeutic Use and Abuse

Psychiatry and Clinical Psychopharmacology
Background: Pregabalin, prescribed for various neurological and psychiatric conditions, has demonstrated increasing potential for abuse. Despite its psychoactive effects and growing misuse, pregabalin remains absent from standard urine drug screening ...
Saliha Aksun, Başak Bağci, Oğuz Karalar, Murat Aksun, Barış Karadaş , Faruk Yavuz, Aslı Tuğba Esen, Mert Üğe, Figen Narin   +8 more
doaj  

Incidence of somnolence and dizziness induced by mirogabalin and pregabalin under opioid treatment: a single-center observational study

Journal of Pharmaceutical Health Care and Sciences
Background The gabapentinoids pregabalin and mirogabalin are utilized to treat neuropathic pain, especially in patients with cancer receiving opioid analgesics. Pregabalin combined with strong opioids increases somnolence and dizziness, while mirogabalin
Hitoshi Iwasaki, Hiroshi Kato, Takenao Koseki, Masashi Kondo, Shigeki Yamada   +4 more
doaj   +1 more source

Status of Pregabalin Misuse in India – Emphasizing the Pressing Need for Intervention: An Integrative Review

Indian Journal of Social Psychiatry
Pregabalin, a gamma-aminobutyric acid-analog compound, is widely used for its anticonvulsant, analgesic, anxiolytic, and euphoric effects. Globally growing evidence suggests that pregabalin misuse is an emerging public health concern. Regulatory measures
Jawahar Singh, Gayatri Bhatia, Bharat Udey, Soumya Swaroop Sahoo   +3 more
doaj   +1 more source

A case report of pregabalin misuse leading to drug dependence

Frontiers in Psychiatry
Pregabalin misuse and dependence have become emerging concerns in recent years, particularly in regions where traditional drug-related crimes have been curbed, prompting users to seek alternative substances.
Yaan Luo, Yaan Luo, Xiafeng Zhou, Xiafeng Zhou, Ao Xiang, Ao Xiang, Yaqi Zeng, Yaqi Zeng, Jing Luo, Jing Luo, Bojie Zhou, Bojie Zhou, Nana Guo, Nana Guo, Xuhui Zhou   +14 more
doaj   +1 more source

Pregabalin acts on Na+–Ca2+ exchanger, which promotes Ca2+ extrusion from human Merkel cell line

PAIN Reports
. Introduction:. Pregabalin, a first-line treatment for neuropathic pain, binds to the voltage-gated calcium channel auxiliary subunit alpha2delta-1, reducing neurotransmitter release.
Rumi Kaneko, Takehito Ouchi, Maki Kimura, Hidetaka Kuroda, Tatsuya Ichinohe, Yoshiyuki Shibukawa   +5 more
doaj   +1 more source

Evaluation of the effect of pregabalin on simulated driving ability using a driving simulator in healthy male volunteers

International Journal of General Medicine, 2014
Tomoaki Tujii, Win Thiri Kyaw, Hirotaka Iwaki, Noriko Nishikawa, Masahiro Nagai, Madoka Kubo, Masahiro Nomoto Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Tohon Ehime, Japan Abstract: Pregabalin, a ...
Tujii T, Kyaw WT, Iwaki H, Nishikawa N, Nagai M, Kubo M, Nomoto M   +6 more
doaj  

Association of perioperative initiation of gabapentin versus pregabalin with kidney function: a target trial emulation study

Frontiers in Medicine
BackgroundGabapentinoids, such as gabapentin and pregabalin, are opioid substitutes commonly included in perioperative multimodal analgesia regimens. We investigated whether the initiation of gabapentin and pregabalin during the perioperative period have
Yanfang He, Liqian Mo, Juan Li, Dongying Lu, Jinlei Niu, Ying Li, Qiying Zeng, Yueming Gao   +7 more
doaj   +1 more source

Pregabalin Monotherapy for Chronic Pain Associated with Osteoarthritis in Working Dogs: A Retrospective Study of 21 Cases. [PDF]

Animals (Basel)
Lee J, Park G, Yoo J, Ahn DG, Lee I.
europepmc   +1 more source