Results 21 to 30 of about 26,979 (243)

Do gabapentin or pregabalin directly modulate the µ receptor? [PDF]

open access: yesPeerJ, 2021
Background Pregabalin and gabapentin improve neuropathic pain symptoms but there are emerging concerns regarding their misuse. This is more pronounced among patients with substance use disorder, particularly involving opioids.
Preeti Manandhar   +4 more
doaj   +2 more sources

Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]

open access: yes, 2013
Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert   +19 more
core   +2 more sources

The Effects of Prenatal Exposure to Pregabalin on the Development of Ventral Midbrain Dopaminergic Neurons

open access: yesCells, 2022
Pregabalin is widely used as a treatment for multiple neurological disorders; however, it has been reported to have the potential for misuse. Due to a lack of safety studies in pregnancy, pregabalin is considered the last treatment option for various ...
Walaa F. Alsanie   +15 more
doaj   +1 more source

THE ANALGESIC EFFECT OF PREGABALIN, A COMPARATIVE STUDY WITH MORPHINE [PDF]

open access: yesZagazig University Medical Journal, 2014
Objectives: this study was designed to assess and compare the effects of pregabalin and morphine on acute thermal pain and on nerve injury associated pain (chronic neuropathic pain).
Hassan .Shabayek   +3 more
doaj   +1 more source

Pregabalin abuse in adolescence: a case series

open access: yesThe Turkish Journal of Pediatrics, 2022
Background. Pregabalin is an inhibitor of gamma-aminobutyric acid (GABA) and can be abused, especially by polydrug abuser adults. Drug abuse is one of the many risky behaviors that can be seen during adolescence.
Burcu Ersöz Alan   +2 more
doaj   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Suicidal ideation and behavior among subjects with substance abuse disorder related to pregabalin

open access: yesMiddle East Current Psychiatry, 2022
Background Although pregabalin abuse is increasing worldwide and may be associated with increased suicidal ideation and behavior, few studies were done in Egypt searching for the effect of pregabalin on suicide.
Abdallah Saad Ibrahim   +4 more
doaj   +1 more source

The Effect of Pregabalin on the Minimum Alveolar Concentration of Sevoflurane: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

open access: yesFrontiers in Medicine, 2022
BackgroundPregabalin is commonly used perioperatively to reduce post-operative pain and opioid consumption and to prevent the development of chronic pain.
Johannes Müller   +5 more
doaj   +1 more source

Pregabalin for Postoperative pain in patients undergoing spinal surgery: A Dose ranging randomized clinical study

open access: yesМедицина болю, 2023
Background: The efficacy of pregabalin in acute post-surgical pain management is well demonstrated. As, the use of pregabalin is officially not approved and hence, there is no dosing guideline as well.
Palak Goel   +5 more
doaj   +1 more source

The preemptive effects of oral pregabalin on perioperative pain management in lower limb orthopedic surgery: a systematic review and meta-analysis

open access: yesJournal of Orthopaedic Surgery and Research, 2022
Background To systematically review the literature and provide a comprehensive understanding of the preemptive effects of oral pregabalin on perioperative pain management in lower limb orthopedic surgery. Method We searched three electronic databases for
Zhao Chen   +4 more
doaj   +1 more source

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