Results 21 to 30 of about 31,350 (256)
Molecular Psychiatry, 2021 The gabapentinoids, gabapentin, and pregabalin, target the α2δ subunits of voltage-gated calcium channels. Initially licensed for pain and seizures, they have become widely prescribed drugs.
James S W Hong +7 more
semanticscholar +1 more source
Pain and Therapy, 2022 Objective To systematically evaluate the clinical efficacy of pregabalin and gabapentin in the treatment of postherpetic neuralgia (PHN), including the difference in pain control and occurrence of adverse reactions.
Xing Cao +5 more
semanticscholar +1 more source
Pregabalin administration in patients with fibromyalgia: a Bayesian network meta-analysis
Scientific Reports, 2022 Several studies investigated the effectiveness and the safety of different doses of pregabalin in fibromyalgia. However, the optimal protocol remains controversial.
Filippo Migliorini +5 more
semanticscholar +1 more source
Biomedicines, 2022 Neuropathic pain is often closely associated with nerve injury or inflammation, and the role of traditional nonsteroidal anti-inflammatory drugs as adjuvants for treating chemotherapy-induced peripheral neuropathic pain remains unclear.
Yurong Ma +6 more
semanticscholar +1 more source
Atención Primaria, 2021 Aim This SR aims to assess the effectiveness of pregabalin and gabapentin on pain and disability caused by acute sciatica and the adverse events associated with their clinical use. Design Systematic review.
María Soledad Giménez-Campos +5 more
semanticscholar +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Effects of pregabalin and gabapentin on postoperative pain and opioid consumption after laparoscopic cholecystectomy [PDF]
Korean Journal of Anesthesiology, 2017 BackgroundGabapentin and pregabalin are antiepileptic drugs that are also used for chronic pain treatment. This study evaluated the effects of pregabalin and gabapentin on postoperative pain in patients undergoing laparoscopic cholecystectomy.MethodsA ...
Mohammad Eidy +5 more
doaj +1 more source
Renal Replacement Therapy, 2022 Background Severe pregabalin intoxication may cause serious symptoms, such as coma. Since pregabalin is a small molecule with no protein binding sites and has low volume of distribution, hemodialysis can be effective in eliminating pregabalin from the ...
Takashi Shimazui +8 more
doaj +1 more source
Do gabapentin or pregabalin directly modulate the µ receptor? [PDF]
PeerJ, 2021 Background Pregabalin and gabapentin improve neuropathic pain symptoms but there are emerging concerns regarding their misuse. This is more pronounced among patients with substance use disorder, particularly involving opioids.
Preeti Manandhar +4 more
doaj +2 more sources
Cells, 2022 Pregabalin is widely used as a treatment for multiple neurological disorders; however, it has been reported to have the potential for misuse. Due to a lack of safety studies in pregnancy, pregabalin is considered the last treatment option for various ...
Walaa F. Alsanie +15 more
doaj +1 more source