Results 31 to 40 of about 31,350 (256)

Pregabalin abuse in adolescence: a case series

The Turkish Journal of Pediatrics, 2022
Background. Pregabalin is an inhibitor of gamma-aminobutyric acid (GABA) and can be abused, especially by polydrug abuser adults. Drug abuse is one of the many risky behaviors that can be seen during adolescence.
Burcu Ersöz Alan, Melis Pehlivantürk Kızılkan, Sinem Akgül   +2 more
doaj   +1 more source

Augmentation with pregabalin in schizophrenia

European Psychiatry, 2010
IntroductionAnxiety is a core symptom of schizophrenia which elicits significant subjective burden of disease and contributes to treatment resistance in schizophrenia. Anxious syndromes might be attributed to incompletely remitted delusions, the negative syndrome, depressive episodes, panic attacks, social phobia, avoidance after hospitalization and ...
Susanne, Englisch, Andrea, Esser, Frank, Enning, Sarah, Hohmann, Heike, Schanz, Mathias, Zink   +5 more
openaire   +2 more sources

Mirogabalin: could it be the next generation gabapentin or pregabalin?

The Korean Journal of Pain, 2021
Except for carbamazepine for trigeminal neuralgia, gabapentinoid anticonvulsants have been the standard for the treatment of neuropathic pain. Pregabalin, which followed gabapentin, was developed with the benefit of rapid peak blood concentration and ...
Jae-Yeon Kim, S. Abdi, B. Huh, Kyung-Hoon Kim   +3 more
semanticscholar   +1 more source

Suicidal ideation and behavior among subjects with substance abuse disorder related to pregabalin

Middle East Current Psychiatry, 2022
Background Although pregabalin abuse is increasing worldwide and may be associated with increased suicidal ideation and behavior, few studies were done in Egypt searching for the effect of pregabalin on suicide.
Abdallah Saad Ibrahim, Reem Hassan Bayomy, Ramadan Abdelbr Hussein, Usama Mahmoud Yousef, Waleed Eleraky Elazab   +4 more
doaj   +1 more source

Mirogabalin vs pregabalin for chemotherapy-induced peripheral neuropathy in pancreatic cancer patients

BMC Cancer, 2021
The prognosis of pancreatic cancer (PC) has been improved by new chemotherapy regimens (combination of 5-fluorouracil, oxaliplatin, irinotecan, and leucovorin (FOLFIRINOX) or gemcitabine plus nab-paclitaxel (GnP)).
M. Sugimoto, T. Takagi, R. Suzuki, Naoki Konno, H. Asama, Yuki Sato, Hiroki Irie, Y. Okubo, Jun Nakamura, Mika Takasumi, M. Hashimoto, T. Kato, R. Kobashi, T. Hikichi, H. Ohira   +14 more
semanticscholar   +1 more source

The Effect of Pregabalin on the Minimum Alveolar Concentration of Sevoflurane: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Frontiers in Medicine, 2022
BackgroundPregabalin is commonly used perioperatively to reduce post-operative pain and opioid consumption and to prevent the development of chronic pain.
Johannes Müller, Walter Plöchl, Paul Mühlbacher, Alexandra Graf, Thomas Stimpfl, Thomas Hamp   +5 more
doaj   +1 more source

Pregabalin as a Pain Therapeutic: Beyond Calcium Channels

Frontiers in Cellular Neuroscience, 2020
Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin (“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA metabolism.
Sascha R. A. Alles, S. Cain, T. Snutch
semanticscholar   +1 more source

The combined analgesic effect of pregabalin and morphine in the treatment of pancreatic cancer pain, a retrospective study

Cancer Medicine, 2021
Pregabalin is commonly used to relieve neuropathic pain. However, data are lacking on its efficacy for the treatment of chronic cancer pain. The purpose of this study was to determine the analgesic efficacy of pregabalin combined with morphine in the ...
J. Dai, L. Teng, Liuyuan Zhao, Huichao Zou   +3 more
semanticscholar   +1 more source

Switching From Pregabalin to Mirogabalin in Patients with Peripheral Neuropathic Pain: A Multi-Center, Prospective, Single-Arm, Open-Label Study (MIROP Study)

Pain and Therapy, 2021
Introduction Mirogabalin, which is a selective ligand of the α 2 δ subunit of voltage-gated Ca 2+ channels, was recently approved in Japan for peripheral neuropathic pain.
Y. Kimura, S. Yamaguchi, Takahiro Suzuki, J. Kato, Satoko Chiba, N. Hirakawa, K. Yamaguchi, Y. Tanabe, H. Takatsuna, Yusuke Kenyoshi, K. Shiosakai, Miyoshi Sakai, M. Iseki   +12 more
semanticscholar   +1 more source

Pregabalin for Postoperative pain in patients undergoing spinal surgery: A Dose ranging randomized clinical study

Медицина болю, 2023
Background: The efficacy of pregabalin in acute post-surgical pain management is well demonstrated. As, the use of pregabalin is officially not approved and hence, there is no dosing guideline as well.
Palak Goel, Anshu S.S. Kotia, Anil Kumar, Mona Bana, Reena Meena, Tarun Singh   +5 more
doaj   +1 more source