Results 51 to 60 of about 27,995 (239)

A comparative study of intravenous fentanyl, oral pregabalin, and a combination of both for attenuation of hemodynamic response to laryngoscopy and tracheal intubation

MRIMS Journal of Health Sciences
Background Responses due to laryngoscopy and endotracheal intubation have an effect on blood pressure, heart rate, catecholamines, and oxygen demand of myocardium. These transient changes may affect those with known cardiovascular disease.
Sarayu Ramamurthy, Guruprasad Bettaswamy
doaj   +1 more source

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT

Health Technology Assessment, 2022
Background: The mainstay of treatment for diabetic peripheral neuropathic pain is pharmacotherapy, but the current National Institute for Health and Care Excellence guideline is not based on robust evidence, as the treatments and their combinations have ...
Solomon Tesfaye, Gordon Sloan, Jennifer Petrie, David White, Mike Bradburn, Tracey Young, Satyan Rajbhandari, Sanjeev Sharma, Gerry Rayman, Ravikanth Gouni, Uazman Alam, Steven A Julious, Cindy Cooper, Amanda Loban, Katie Sutherland, Rachel Glover, Simon Waterhouse, Emily Turton, Michelle Horspool, Rajiv Gandhi, Deirdre Maguire, Edward Jude, Syed Haris Ahmed, Prashanth Vas, Christian Hariman, Claire McDougall, Marion Devers, Vasileios Tsatlidis, Martin Johnson, Didier Bouhassira, David L Bennett, Dinesh Selvarajah   +31 more
doaj   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source

Prevalence and risk factors of pregabalin misuse among patients with substance use disorder

Al-Azhar Assiut Medical Journal, 2019
Background Pregabalin use disorder is an alarming phenomenon demonstrated in many countries. Some countries classified it as a class C controlled substance in a schedule V controlled substance.
Amgad A.M Gabr
doaj   +1 more source

Pregabalin-induced rhabdomyolysis: a case series and literature analysis

Journal of International Medical Research
Pregabalin is a prescription medicine that has recently been approved for individuals who suffer from fibromyalgia, neuropathic pain, anxiety disorder, or epilepsy. Pregabalin has the side effects of dizziness, sleepiness, and angioedema.
Wenjing Zhai, Hao Liu, Jinrui Li, Haili Xin   +3 more
doaj   +1 more source

Comparative Evaluation of Two Different Doses of Pre-Emptive Oral Pregabalin on Duration of Spinal Anesthesia and Postoperative Pain

Archives of Anesthesia and Critical Care, 2021
Background: Pregabalin provides good postoperative analgesia in nociceptive stimuli. Various studies show that preemptive oral pregabalin reduces acute postoperative pain. We conducted a study to evaluate the efficacy of two different doses of pregabalin
Neha Amey Panse, Kavita Udaykumar Adate, Sachin Harishchandra Panchal   +2 more
doaj   +1 more source

การใช้ยาพรีกาบาลิน (Pregabalin) ก่อนและหลังผ่าตัด [PDF]

, 2021
Nowadays, there are a large number of studies on perioperative use of pregabalin. This article describes the effects of pregabalin on acute postoperative pain, chronic postsurgical pain (CPSP) and preoperative anxiety, and how to optimize perioperative ...
Charoenporn, Benjalak
core  

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

Drug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani, Kirsten L. Rock, Kathleen Rice‐Davies, Rebecca Lo, Benedict Morley, Stephen Morley, Caroline S. Copeland   +6 more
wiley   +1 more source

Pregabalin and gabapentin associated with depression and suicidal ideation

, 2018
Abuse of pregabalin and gabapentin for their euphoric effects may only be part of the story.1 Pregabalin has also been associated with suicidal ideation234 and depressed mood.45 In a small case series, approximately 10% of patients recently started on ...
King, Michelle A
core   +1 more source