Results 71 to 80 of about 27,995 (239)

Comparison of Two Different Pulsed Radiofrequency Modes for Prevention of Postherpetic Neuralgia in Elderly Patients with Acute/Subacute Trigeminal Herpes Zoster

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Trigeminal postherpetic neuralgia (PHN) is often refractory to treatment. Pulsed radiofrequency (PRF) neuromodulation can help in preventing PHN after herpes zoster. This study aimed to compare the efficacy and safety of two different PRF modes on gasserian ganglion neuromodulation in elderly patients with acute/subacute trigeminal ...
Cheng‐Fu Wan, Tao Song
wiley   +1 more source

“Just give me pregabalin, doctor”: pregabalin use disorder in two undocumented migrants from North Africa

open access: yes, 2023
Introduction Pregabalin is a widely prescribed medication for various medical conditions, including neuropathic pain and anxiety disorders. Recently, several studies have shown an increase in the recreational use of pregabalin, particularly among ...
Catarina Cunha   +2 more
core   +1 more source

Do preclinical seizure models predict success or failure in anti‐seizure drug development? A retrospective analysis of 89 compounds with divergent clinical outcomes for epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Anti‐seizure medication (ASM) discovery remains a major challenge despite over 30 commercially available options. One persistent obstacle for any promising candidate compound to successfully move from preclinical study to clinical approval has been the ambiguity in preclinical model selection.
Wolfgang Löscher   +1 more
wiley   +1 more source

Pregabalin Addiction: Case Report of a Young Adult [PDF]

open access: yes, 2020
Pregabalin has been used widely for the treatment of neuropathic pain, generalized anxiety disorders and epilepsy. Data is scarce and much is not known about the addictive potential of pregabalin.
Nitin Chaudhary, Sapna Jain
core   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

open access: yesEpilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar   +4 more
wiley   +1 more source

Pregabalin in acute and chronic pain

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2011
Pregabalin is a gamma-amino-butyric acid analog shown to be effective in several models of neuropathic pain, incisional injury, and inflammatory injury. In this review, the role of pregabalin in acute postoperative pain and in chronic pain syndromes has ...
Dalim Kumar Baidya   +3 more
doaj   +1 more source

Preemptive Effect of Oral Pregabalin on Post-Operative Pain Control in Lower Limb Fractures [PDF]

open access: yes
Background & Objectives: dolnortnccnU postoperative pain can cause many adverse effects such as tachycardia, hypertension, myocardial ischemia, decreased alveolar ventilation and poor wound healing.
اخوان اکبری, قدرت   +3 more
core  

Outcomes of patients with post‐stroke epilepsy: A scoping review on quality of life, readmissions, costs, seizure recurrence, and medication adherence

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Post‐stroke epilepsy (PSE) affects ≈10% of patients with stroke and is associated with adverse health and economic outcomes. We aimed to review published literature on health and economic outcomes for patients with PSE, with a specific focus on quality of life, hospital readmissions, healthcare costs, seizure recurrence, and ...
Nega Dagnew Baye   +5 more
wiley   +1 more source

Perioperative gabapentin and pregabalin in cardiac surgery: a systematic review and meta-analysis

open access: yesRevista Brasileira de Anestesiologia
Objectives: Sternotomy for cardiac surgeries causes significant postoperative pain and when not properly managed may cause significant morbidity. As neuropathic pain is a significant component here, gabapentin and pregabalin may be effective in these ...
Souvik Maitra   +3 more
doaj   +1 more source

Bridging the Gap in Headache Care: Insights From the International Headache Society Survey in Nepal

open access: yesHealth Care Science, EarlyView.
Distinct relationships exist between urban and rural healthcare settings and key components of headache care in Nepal. Urban providers are more likely to be trained in migraine management, prescribe migraine‐specific medications, higher headache patient load and serve more specific adult group.
Rajeev Ojha   +13 more
wiley   +1 more source

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