Results 81 to 90 of about 31,350 (256)
Preparation and characterization of ethylcellulose microspheres for sustained-release of pregabalin
Research in Pharmaceutical Sciences, 2020 Background and purpose: Pregabalin is used in the treatment of epilepsy, chronic pain, and other psychological disorders. Preparation of pregabalin in the sustained-release formulation will enhance patient compliance and reduce the incidence of side ...
H. Yasin, B. Al-Taani, M. Salem
semanticscholar +1 more source
Epilepsia Open, EarlyView.Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar +4 more
wiley +1 more source
Pregabalin in acute and chronic pain
Journal of Anaesthesiology Clinical Pharmacology, 2011 Pregabalin is a gamma-amino-butyric acid analog shown to be effective in several models of neuropathic pain, incisional injury, and inflammatory injury. In this review, the role of pregabalin in acute postoperative pain and in chronic pain syndromes has ...
Dalim Kumar Baidya +3 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho +8 more
wiley +1 more source
Angiosarcoma of the Scalp Presenting With Eyelid Edema: A Diagnostic Pitfall of Eyelid Biopsy
JEADV Clinical Practice, EarlyView.ABSTRACT Angiosarcoma of the scalp is a rare but aggressive vascular malignancy that may present with nonspecific clinical findings, potentially leading to delayed diagnosis. Eyelid edema is an uncommon initial manifestation and has been suggested to result from direct tumor infiltration or lymphatic obstruction.
Sayo Komiyama +7 more
wiley +1 more source
Molecules, 2020 Analgesic drugs in a combination-form can achieve greater efficacy with lesser side effects compared to either drug alone. The combination of drugs acting at different targets or mechanisms of action has been recognized as an alternative approach for ...
Sarinee Leksiri +5 more
semanticscholar +1 more source
Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough
The Laryngoscope, EarlyView.The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen +3 more
wiley +1 more source
Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes
The Laryngoscope, EarlyView.A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar +6 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Indira Garcia‐Cordero +12 more
wiley +1 more source