Results 61 to 70 of about 26,979 (243)
Perioperative gabapentin and pregabalin in cardiac surgery: a systematic review and meta-analysis
Revista Brasileira de AnestesiologiaObjectives: Sternotomy for cardiac surgeries causes significant postoperative pain and when not properly managed may cause significant morbidity. As neuropathic pain is a significant component here, gabapentin and pregabalin may be effective in these ...
Souvik Maitra +3 more
doaj +1 more source
Pregabalin and gabapentin associated with depression and suicidal ideation
, 2018 Abuse of pregabalin and gabapentin for their euphoric effects may only be part of the story.1 Pregabalin has also been associated with suicidal ideation234 and depressed mood.45 In a small case series, approximately 10% of patients recently started on ...
King, Michelle A
core +1 more source
Epilepsia, EarlyView.Abstract Objective Using a Dutch insurance claims registry, we examine whether people with epilepsy have an increased risk of major ischemic cardiovascular events or death compared to people without epilepsy. We also assess whether this risk differs between users of enzyme‐modulating and non‐enzyme‐modulating antiseizure medications (ASMs).
Paola Vassallo +4 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives The aim of the present study was to investigate the analgesic effects of repetitive transcranial magnetic stimulation over the primary motor cortex (M1‐rTMS) using different stimulation parameters to explore the optimal stimulus condition for treating neuropathic pain.
Nobuhiko Mori +5 more
wiley +1 more source
Oral self-administration of pregabalin in a mouse model and the resulting drug addiction features
Saudi Pharmaceutical JournalPrescription drug abuse is an issue that is rapidly growing globally. Pregabalin, an anticonvulsant, analgesic, and anxiolytic medication, is effective in the management of multiple neurological disorders; however, there is increasing concern regarding ...
Yusuf S. Althobaiti
doaj +1 more source
Preemptive Effect of Oral Pregabalin on Post-Operative Pain Control in Lower Limb Fractures [PDF]
Background & Objectives: dolnortnccnU postoperative pain can cause many adverse effects such as tachycardia, hypertension, myocardial ischemia, decreased alveolar ventilation and poor wound healing.
اخوان اکبری, قدرت +3 more
core
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Epilepsia, EarlyView.Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx +192 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley +1 more source
Pregabalin in acute and chronic pain
Journal of Anaesthesiology Clinical Pharmacology, 2011 Pregabalin is a gamma-amino-butyric acid analog shown to be effective in several models of neuropathic pain, incisional injury, and inflammatory injury. In this review, the role of pregabalin in acute postoperative pain and in chronic pain syndromes has ...
Dalim Kumar Baidya +3 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Pediatric drug‐resistant epilepsy (DRE) remains a significant clinical challenge, with few effective pharmacological options. This European multicenter retrospective study assessed the real‐world efficacy, tolerability, and retention of off‐label cenobamate (CNB) in 108 children and adolescents with DRE (median age: 13.83 years, range 3.9–19.8)
Konstantin L. Makridis +14 more
wiley +1 more source