Results 11 to 20 of about 40,857 (285)
Review of the Treatment of Restless Legs Syndrome: Focus on Gabapentin Enacarbil [PDF]
Journal of Central Nervous System Disease, 2012 The FDA approved gabapentin enacarbil in 2011 as the first non-dopaminergic agent for the treatment of restless legs syndrome (RLS) symptoms. Although gabapentin enacarbil is a pro-drug of gabapentin, its pharmacokinetics differ. Absorption of gabapentin
Rachel A. Burke, Michele A. Faulkner
doaj +2 more sources
Development and Evaluation of Topical Gabapentin Formulations [PDF]
Pharmaceutics, 2017 Topical delivery of gabapentin is desirable to treat peripheral neuropathic pain conditions whilst avoiding systemic side effects. To date, reports of topical gabapentin delivery in vitro have been variable and dependent on the skin model employed ...
Christopher J. Martin +3 more
doaj +3 more sources
Epilepsia, 1999 Summary:Gabapentin (GBP) is a antiepileptic drug (AED) indicated as adjunct therapy for treatment of partial seizures, with and without secondary generalization, in patients 12 and older with epilepsy. GBP (1‐(aminomethyl) cyclohexaneacetic acid) is structurally related to γ‐aminobutyric acid (GABA), which readily crosses the blood‐brain barrier ...
openaire +2 more sources
Global Medical & Health Communication, 2020 Diabetic neuropathy is the most common microvascular complication of diabetes mellitus (DM) occurring in 60–70% of the world's DM population, 40% of the DM population in Asia, and 41% of the DM population in Indonesia.
Mochamad Firdaus Bhuanaputra +2 more
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection [PDF]
, 2017 Gabapentin is well known for its pain control and antiepileptic effect, but its antiemetic effect is poorly investigated. Here we report on effective gabapentin use for refractory vomiting after craniotomy in two children with medulloblastoma in the ...
Tsai, Ko-Chun;Yang, Yung-Li;Fan, Pi-Chuan +1 more
core +1 more source
Effect of pretreatment with gabapentin on withdrawal movement associated with intravenous rocuronium injection [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundThe major disadvantage of rocuronium is the withdrawal movement associated with its injection. The analgesic effect of perioperative gabapentin has been evaluated.
Jin Sun Yoon +6 more
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The effects of gabapentin pretreatment on brain injury induced by focal cerebral ischemia/reperfusion in the rat [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundExperimental studies have shown that gabapentin can reduce neuronal injury in the setting of cerebral ischemia, but the mechanisms have not yet been clearly determined.
Yoo-kyung Kim +4 more
doaj +1 more source
Gabapentin Enacarbil: Pharmacotherapy of Restless Legs Syndrome [PDF]
, 2010 Restless Legs Syndrome (RLS) is a prevalent sleep-associated movement disorder greatly affecting patients’ quality of life (QoL). Several drugs can be used to control this condition although the first-line dopamine agents often cause adverse effects. Non-
Ruth Jones +5 more
core +1 more source
Pharmacokinetics and pharmacodynamics of repeat dosing of gabapentin in adult horses
Journal of Veterinary Internal Medicine, 2022 Background The repeated administration of high doses of gabapentin may provide better analgesia in horses than current clinical protocols. Hypothesis and Objectives Administration of gabapentin at 40 and 120 mg/kg PO q 12 h for 14 days will not alter ...
Jenifer R. Gold +4 more
doaj +1 more source