Results 11 to 20 of about 44,091 (186)
Objective: To identify case reports and studies regarding patients who abused, became dependent on, or experienced withdrawal from gabapentin. Data Sources: A PubMed literature search (1993 to October 2015) was performed using the search terms ...
Tracey L, Mersfelder, William H, Nichols
core +6 more sources
Review of the Treatment of Restless Legs Syndrome: Focus on Gabapentin Enacarbil
The FDA approved gabapentin enacarbil in 2011 as the first non-dopaminergic agent for the treatment of restless legs syndrome (RLS) symptoms. Although gabapentin enacarbil is a pro-drug of gabapentin, its pharmacokinetics differ. Absorption of gabapentin
Rachel A. Burke, Michele A. Faulkner
doaj +2 more sources
Gabapentin is a second-generation antiepileptic drug characterized by few antiepileptic indications, with very good interaction profile in polytherapy.
Andrea E. Cavanna
core +4 more sources
The cyclooxygenase-2 inhibitor, rofecoxib, was a popular analgesic adjuvant for improving perioperative pain management. We designed this placebo-controlled study to test the hypothesis that gabapentin could produce similar reductions in postoperative pain and opioid analgesic usage, thereby improving the recovery process.
Turan, A +6 more
core +4 more sources
Characterizing the Relationship Between Nonmedical Use of Gabapentin and Gabapentin Prescribing Among Individuals With Opioid Use Disorder. [PDF]
Objectives: Persons with opioid use disorder (OUD) are at elevated risk for engaging in the nonmedical use (NMU) of gabapentin.
Ellis MS +4 more
europepmc +2 more sources
Summary:Gabapentin (GBP) is a antiepileptic drug (AED) indicated as adjunct therapy for treatment of partial seizures, with and without secondary generalization, in patients 12 and older with epilepsy. GBP (1‐(aminomethyl) cyclohexaneacetic acid) is structurally related to γ‐aminobutyric acid (GABA), which readily crosses the blood‐brain barrier ...
openaire +2 more sources
Background: Gabapentin attenuates the haemodynamics, decreases the catecholamine release and has a neuroprotective effect. The aim of the present study was to assess the effect of gabapentin in patients with supratentorial brain tumours undergoing ...
Rabie Soliman, Gomaa Zohry
doaj +3 more sources
ABSTRACT:Gabapentin is a novel antiepileptic drug that has recently been introduced in Canada. Although its mechanism of action remains to be defined gabapentin is effective in a number of seizure models which predict its efficacy in partial and tonic-clonic seizures. Clinical studies support the clinical efficacy of gabapentin as adjunctive therapy in
openaire +2 more sources
Effect of pretreatment with gabapentin on withdrawal movement associated with intravenous rocuronium injection [PDF]
BackgroundThe major disadvantage of rocuronium is the withdrawal movement associated with its injection. The analgesic effect of perioperative gabapentin has been evaluated.
Jin Sun Yoon +6 more
doaj +1 more source
Dear Editor, I read with interest the article entitled Effect of Gabapentin on Morphine Consumption and Pain after Surgical Debridement of Burn Wounds: A Double-Blind Randomized Clinical Trial Study and was impressed by the scientific rigor and level of detailed observation. This is especially admirable in a study performed at the front line of burn
openaire +2 more sources

