Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid-Related Adverse Events Following Surgery for Breast Cancer. [PDF]
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Lai JH +12 more
europepmc +2 more sources
Review of the Treatment of Restless Legs Syndrome: Focus on Gabapentin Enacarbil
The FDA approved gabapentin enacarbil in 2011 as the first non-dopaminergic agent for the treatment of restless legs syndrome (RLS) symptoms. Although gabapentin enacarbil is a pro-drug of gabapentin, its pharmacokinetics differ. Absorption of gabapentin
Rachel A. Burke, Michele A. Faulkner
doaj +2 more sources
The Effect of Once-Daily Gabapentin Extended Release Formulation in Patients With Postamputation Pain [PDF]
ObjectivesTo compare gabapentin extended-release, a gastro-retentive formulation, in relieving postamputation pain among gabapentin-experienced and gabapentin-naïve patients.DesignOpen-labeled pilot study.SubjectsSixteen patients with postamputation pain
Nebojsa Nick Knezevic +9 more
doaj +2 more sources
Comparative Effectiveness and Safety of Original Gabapentin and Generic Gabapentin in Treating Patients with Neuropathic Pain at Siriraj Hospital, Bangkok, Thailand [PDF]
Background: Neuropathic pain (NP) develops as a consequence of a lesion or disease affecting the somatosensory system. Patients with severe NP usually suffer from pain and may need many treatment options.
Rungsan Chaisewikul +3 more
doaj +1 more source
Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough [PDF]
ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Teng T +5 more
europepmc +2 more sources
Review About Gabapentin Misuse, Interactions, Contraindications and Side Effects
Gabriel C Quintero Florida State University – Republic of Panama, Clayton, Panama Abstract: The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications ...
Gabriel C Quintero Garzola
exaly +2 more sources
Comparison effects of pre-emptive gabapentin and meloxicam for postoperative pain in white new zealand rabbits undergoing ovariohysterectomy using the grimace scale [PDF]
The study aimed to evaluate the effectiveness of Gabapentin in controlling postoperative pain in New Zealand white rabbits after ovariohysterectomy.
Hourieh MARGHOUB +2 more
doaj +1 more source
Comparison between the analgesic effect of Tizanidine, Diclofenac and Gabapbentin on experimentally induced acute and chronic pain in male albino rats [PDF]
Background: Pain is an unpleasant sensation experienced when tissues are damaged. Therapeutic management of pain requires consideration of many factors due multiplicity of etiopathogenesis. Objectives: The present study was designed to assess and compare
Amany Zayed +3 more
doaj +1 more source
Prenatal Exposure to Gabapentin Alters the Development of Ventral Midbrain Dopaminergic Neurons
Background: Gabapentin is widely prescribed as an off-label drug for the treatment of various diseases, including drug and alcohol addiction. Approximately 83–95% of the usage of gabapentin is off-label, accounting for more than 90% of its sales in the ...
Walaa F. Alsanie +25 more
doaj +1 more source
Development of a novel niosomal formulation for Gabapentin [PDF]
Background: Gabapentin is an anticonvulsant drug prescribed to treat partial seizures and neuropathic pain. Nisomes as a type of lipid based drug carriers can improve the pharmacokinetic properties of therapeutic agents.
Iman Akbarzadeh +3 more
doaj +1 more source

