Results 41 to 50 of about 44,091 (186)
GABAB Receptors Do Not Mediate the Inhibitory Actions of Gabapentin on the Spinal Reflex in Rats
Journal of Pharmacological Sciences, 2004 The clinical effectiveness of gabapentin for the treatment of epilepsy, spasticity, and neuropathic pain has been established. The mechanisms responsible for those actions, however, are still not clearly understood.
Shinobu Shimizu +3 more
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Gabapentin for Alcohol Use Disorder [PDF]
, 2023 The purpose of this literature review is to determine whether gabapentin is an effective treatment option for alcohol use disorder (AUD). Utilizing data sourced primarily from published clinical trials, gabapentin’s effect on heavy drinking, abstinence ...
Hurst, Monica
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Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin
Brazilian Journal of Nephrology, 2012 INTRODUCTION: Uremic pruritus is common among dialysis patients. Effective treatments are not readily available. Early evidence with antihistamines and gabapentin indicate variable effects.
Diego Marquez +9 more
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Efficacy Of Gabapentin In Trigeminal Neuralgia: A Non-randomized Trial
Journal of Bahria University Medical and Dental College, 2021 Objective: To compare the efficacy of Gabapentin with carbamazepine in Trigeminal Neuralgia. Material/Method: The study was conducted in Agha Khan University Hospital and Abbasi Shaheed Hospital for four months.
Nasir Ali Khan +6 more
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Endogenous GABA Does Not Mediate the Inhibitory Effects of Gabapentin on Spinal Reflexes in Rats
Journal of Pharmacological Sciences, 2004 The novel antiepileptic drug gabapentin was designed as a structural analog of γ-aminobutyric acid (GABA). However, its mechanism of action remains unclear. In the present study, we investigated the effect of gabapentin on spinal reflexes in anesthetized
Shinobu Shimizu +4 more
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Gabapentin enacarbil – clinical efficacy in restless legs syndrome
Neuropsychiatric Disease and Treatment, 2010 Pinky Agarwal1, Alida Griffith1, Henry R Costantino2, Narendra Vaish31Booth Gardner Parkinson’s Center, Kirkland, WA, USA; 2Costantino Consulting, Woodinville, WA, USA; 3Kirkland, WA, USAAbstract: Restless legs syndrome (RLS) is a sleep-related
Pinky Agarwal +3 more
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Perioperative gabapentin and pregabalin in cardiac surgery: a systematic review and meta-analysis
Revista Brasileira de AnestesiologiaObjectives: Sternotomy for cardiac surgeries causes significant postoperative pain and when not properly managed may cause significant morbidity. As neuropathic pain is a significant component here, gabapentin and pregabalin may be effective in these ...
Souvik Maitra +3 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2019 Purpose: Gabapentin, a drug for neuropathic pain, exerts its therapeutic effect via inhibition of the a2d subunit of N-type Ca2+ channels. Thus, finding peptides that specifically displace gabapentin from its binding site may lead to the development of ...
Hanna Skubatz
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Gabapentin Extended-Release ??? Depomed
Drugs in R & D, 2007 Depomed is developing an extended-release (ER) oral formulation of gabapentin, a GABA receptor agonist commonly used for the treatment of epilepsy and seizures, neuropathic pain and hot flushes. Gabapentin ER is based on the company's proprietary AcuForm drug delivery technology, which is part of the Gastric Retention (GR) family of technologies; this ...
openaire +2 more sources
Gabapentin Toxicity in Patients with Chronic Kidney Disease; Series of Our Cases
Turkish Journal of Nephrology, 2019 Gabapentin is an anticonvulsant with analgesic and anxiolytic effects and also an agent used for treatment of a variety of chronic neuropathic pains. Because gabapentin is eliminated solely through the kidney, kidney failure poses a risk for gabapentin ...
Ali KARAGÖZ +4 more
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