Results 61 to 70 of about 47,104 (255)
Gabapentin-Induced Urinary Incontinence: A Rare Side Effect in Patients with Neuropathic Pain
Case Reports in Neurological Medicine, 2015 Gabapentin is a first-line agent for neuropathic pain management and has a favorable safety profile. The literature includes a few cases of gabapentin-induced incontinence, and most of them involved patients with epilepsy who were between the ages of 12 ...
Sibel Kibar +5 more
doaj +1 more source
Comparison of gabapentin with estrogen for treatment of hot flashes in post-menopausal women
Journal of Research in Pharmacy Practice, 2013 Objective: Various non-hormonal agents have been used for the treatment of hot flashes in women with menopause. Some studies have reported that gabapentin appears to be an effective and well-tolerated treatment modality.
Zahra Allameh +2 more
doaj +1 more source
Therapeutic Advances in Chronic Disease, 2020 Background: Gabapentin is recommended for the treatment of chronic refractory cough (CRC). This study aims to identify its therapeutic predictors in a prospective clinical study.
Mengru Zhang +6 more
doaj +1 more source
Gabapentin Enacarbil: Pharmacotherapy of Restless Legs Syndrome
, 2010 Restless Legs Syndrome (RLS) is a prevalent sleep-associated movement disorder greatly affecting patients’ quality of life (QoL). Several drugs can be used to control this condition although the first-line dopamine agents often cause adverse effects. Non-
Ruth Jones +5 more
core +1 more source
Understanding Deformation Behavior and Compression Speed Effect in Gabapentin Compacts
, 2021 Deformation mechanism and strain rate sensitivity of gabapentin powder was investigated in this work. Heckel analysis, specific surface area and indentation hardness measurements revealed an intermediate yield pressure and brittle fracture as the ...
Buckner, Ira S +3 more
core +1 more source
Epilepsia, EarlyView.Abstract Anti‐seizure medication (ASM) discovery remains a major challenge despite over 30 commercially available options. One persistent obstacle for any promising candidate compound to successfully move from preclinical study to clinical approval has been the ambiguity in preclinical model selection.
Wolfgang Löscher +1 more
wiley +1 more source
Mechanisms of the Antinociceptive Action of Gabapentin
, 2009 . Gabapentin, a γ-aminobutyric acid (GABA) analogue anticonvulsant, is also an effective analgesic agent in neuropathic and inflammatory, but not acute, pain systemically and intrathecally.
鄭仁坤;邱麗珠 +1 more
core
Epilepsia, EarlyView.Abstract Objective To describe treatment decisions after first anti‐seizure medication (ASM) failure in focal epilepsy and describe how they have changed across two trial eras, and whether observed prescribing matched clinicians stated preferences. Methods We analyzed the focal epilepsy cohorts from two UK pragmatic, randomized trials, Standard and New
Isaac J. Egesa +4 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar +4 more
wiley +1 more source
Myoclonus in renal failure: Two cases of gabapentin toxicity
Epilepsy and Behavior Case Reports, 2014 Gabapentin, an AED approved for the adjunctive treatment of partial seizures with/without secondary generalization and for the treatment of postherpetic neuralgia, is frequently used off-label for the treatment of both psychiatric and pain disorders ...
Kenneth R. Kaufman +4 more
doaj +1 more source