Results 61 to 70 of about 44,091 (186)

Pregabalin and gabapentin associated with depression and suicidal ideation

open access: yes, 2018
Abuse of pregabalin and gabapentin for their euphoric effects may only be part of the story.1 Pregabalin has also been associated with suicidal ideation234 and depressed mood.45 In a small case series, approximately 10% of patients recently started on ...
King, Michelle A
core   +1 more source

Comparison Effect of Pre-Emptive Gabapentin and Oxycodone on Pain After Abdominal Hysterectomy: A Double Blind Randomized Clinical Trial

open access: yesActa Medica Iranica, 2018
Gabapentin is popular analgesic adjuvants for improving postoperative pain management. The aim of this study was to compare the preventive effects of pre-emptive oxycodone and gabapentin on acute pain after elective abdominal hysterectomy.
Valiollah Hassani   +6 more
doaj  

Association of perioperative initiation of gabapentin versus pregabalin with kidney function: a target trial emulation study

open access: yesFrontiers in Medicine
BackgroundGabapentinoids, such as gabapentin and pregabalin, are opioid substitutes commonly included in perioperative multimodal analgesia regimens. We investigated whether the initiation of gabapentin and pregabalin during the perioperative period have
Yanfang He   +7 more
doaj   +1 more source

The use of gabapentin enacarbil in the treatment of restless legs syndrome

open access: yesTherapeutic Advances in Neurological Disorders, 2010
Restless legs syndrome (RLS) is a common sleep-related neurological disorder that is characterized by the urge to move, worsening at rest, improvement with activity, and worsening in the evening and night.
Toby C. Yaltho, William G. Ondo
doaj   +1 more source

Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset.

open access: yesPLoS Medicine, 2020
BackgroundDespite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes.
Elisabetta Patorno   +6 more
doaj   +1 more source

BUMPS: Best use of medicines in pregnancy - Gabapentin.

open access: yes, 2019
This factsheet has been written for members of the public by the UK Teratology Information Service (UKTIS). UKTIS is a not-for-profit organisation funded by Public Health England on behalf of UK Health Departments.

core  

Efficacy of gabapentin for the prevention of postherpetic neuralgia in patients with acute herpes zoster: A double blind, randomized controlled trial.

open access: yesPLoS ONE, 2019
BackgroundPostherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ). Previous trials have reported that gabapentin can relieve chronic neuropathic pain, but its effect on prevention of PHN is unclear.ObjectiveTo assess the ...
Oana Bulilete   +5 more
doaj   +1 more source

Development and Evaluation of Topical Gabapentin Formulations

open access: yesPharmaceutics, 2017
Topical delivery of gabapentin is desirable to treat peripheral neuropathic pain conditions whilst avoiding systemic side effects. To date, reports of topical gabapentin delivery in vitro have been variable and dependent on the skin model employed ...
Christopher J. Martin   +3 more
doaj   +1 more source

Akathisia Induced by Gabapentin Withdrawal

open access: yes, 2011
OBJECTIVE: To report a case of akathisia in a patient with type 2 diabetes after abrupt discontinuation of gabapentin. CASE SUMMARY: A 76-year-old female with type 2 diabetes was admitted for change in mental status, agitation, and restless limb ...
Sharon See, Leslie Hsiung, Erin Hendriks
core   +1 more source

Altered expression of the voltage-gated calcium channel subunit α2δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain. [PDF]

open access: yes, 2014
The auxiliary α2δ-1 subunit of voltage-gated calcium channels is up-regulated in dorsal root ganglion neurons following peripheral somatosensory nerve damage, in several animal models of neuropathic pain.
Sandhu, G   +11 more
core   +1 more source

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