Results 71 to 80 of about 44,091 (186)

A case of gait disturbance caused by low-dose gabapentin

open access: yes, 2016
Megumi Kanao-Kanda, Hirotsugu Kanda, Osamu Takahata, Takayuki Kunisawa Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical University, Asahikawa, Hokkaido, Japan Abstract: Gabapentin, an anticonvulsant agent, is now often used ...
Kunisawa T   +3 more
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Gabapentin-induced severe myopathy

open access: yes, 2007
OBJECTIVE: To report and discuss a case of rhabdomyolysis in an elderly patient with neuropathic pain who was treated with gabapentin. CASE SUMMARY: An 85-year-old diabetic woman was hospitalized for severe pain in her lower limbs and difficulty in ...
TUCCORI, MARCO   +7 more
core   +1 more source

Protein Kinase A–Dependence of the Supraspinally Mediated Analgesic Effects of Gabapentin on Thermal and Mechanical Hypersensitivity

open access: yesJournal of Pharmacological Sciences, 2009
.: We have recently shown that gabapentin generates protein kinase A (PKA)-dependent presynaptic inhibition of GABAergic synaptic transmission in locus coeruleus (LC) neurons only under neuropathic states.
Keiko Takasu   +3 more
doaj   +1 more source

Discriminative Stimulus Effects of Gabapentin [PDF]

open access: yes, 2018
The present study sought to evaluate the discriminative stimulus effects of the anticonvulsant gabapentin in rats trained to discriminate 30.0 mg/kg gabapentin from vehicle in a two-lever drug discrimination task.
Zuidema, Michael
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Pharmacokinetics of gabapentin in cats

open access: yes, 2010
Objective—To determine the pharmacokinetics of gabapentin in cats after IV and oral administration. Animals—6 healthy female adult domestic shorthair cats. Procedures—Gabapentin was administered IV (4 mg/kg) or orally (10 mg/kg) in a crossover randomized
Jan E. Ilkiw   +2 more
core   +1 more source

Gabapentin Inhibits Protein Kinase C Epsilon Translocation in Cultured Sensory Neurons with Additive Effects When Coapplied with Paracetamol (Acetaminophen)

open access: yesThe Scientific World Journal, 2017
Gabapentin is a well-established anticonvulsant drug which is also effective for the treatment of neuropathic pain. Although the exact mechanism leading to relief of allodynia and hyperalgesia caused by neuropathy is not known, the blocking effect of ...
Vittorio Vellani, Chiara Giacomoni
doaj   +1 more source

Gabapentin misuse [PDF]

open access: yesCanadian Medical Association Journal, 2019
Robin, Lennox, Dee, Mangin
openaire   +2 more sources

Use of preoperative gabapentin significantly reduces postoperative opioid consumption: a meta-analysis

open access: yes, 2016
Sudha Arumugam,1 Christine SM Lau,1,2 Ronald S Chamberlain1–3 1Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA; 2Saint George’s University School of Medicine, Grenada, West Indies; 3Department of Surgery, Rutgers ...
Lau CSM, Chamberlain RS, Arumugam S
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Premedication with gabapentin

open access: yes, 2007
BACKGROUND: Gabapentin, an oral non-opioid analgesic, has been used to decrease pain after a variety of surgical procedures. We hypothesized that premedication with gabapentin would minimize tourniquet-related pain in patients receiving IV regional ...
Turan, Alparslan   +3 more
core   +1 more source

Single dose pharmacokinetic equivalence study of two gabapentin preparations in healthy subjects

open access: yes, 2014
Raymond R Tjandrawinata,1 Effi Setiawati,2 Ratih Sofia Ika Putri,2 Danang Agung Yunaidi,2 Fawzia Amalia,2 Liana W Susanto1 1Dexa Laboratories of Biomolecular Sciences, Cikarang, Indonesia; 2PT Equilab International, Bioavailability and Bioequivalence ...
Putri RSI   +5 more
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