Results 91 to 100 of about 47,104 (255)
, 2001 Treatment of patients with anxiety disorders—with and without concurrent depression—is problematic. Gabapentin, a newer antiepileptic drug, is an attractive alternative to the anxiolytics currently in use.
John W. Norton, Emily Quarles
core +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Ichthyotic keratoderma with spasticity, hypomyelination and dysmorphic features (IKSHD; OMIM #618527) is an ultra‐rare neuroichthyosis caused by dominant variants in ELOVL1, the elongase of very‐long‐chain fatty acids required for both the epidermal permeability barrier and central nervous system myelin.
Roxana Pirker +3 more
wiley +1 more source
Development and Evaluation of Topical Gabapentin Formulations
Pharmaceutics, 2017 Topical delivery of gabapentin is desirable to treat peripheral neuropathic pain conditions whilst avoiding systemic side effects. To date, reports of topical gabapentin delivery in vitro have been variable and dependent on the skin model employed ...
Christopher J. Martin +3 more
doaj +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The study aimed to investigate the efficacy of ultrasound‐guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine‐dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD.
Jin Li, Xiang‐Yu Fang
wiley +1 more source
Journal of Pharmacological Sciences, 2009 .: We have recently shown that gabapentin generates protein kinase A (PKA)-dependent presynaptic inhibition of GABAergic synaptic transmission in locus coeruleus (LC) neurons only under neuropathic states.
Keiko Takasu +3 more
doaj +1 more source
Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes
The Laryngoscope, EarlyView.A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar +6 more
wiley +1 more source
Pharmacokinetics of gabapentin in cats
, 2010 Objective—To determine the pharmacokinetics of gabapentin in cats after IV and oral administration. Animals—6 healthy female adult domestic shorthair cats. Procedures—Gabapentin was administered IV (4 mg/kg) or orally (10 mg/kg) in a crossover randomized
Jan E. Ilkiw +2 more
core +1 more source
Supraglottic Botulinum Toxin Injection Improves Symptoms of Laryngeal Sensory Dysfunction
The Laryngoscope, EarlyView.In this retrospective cohort of 80 patients with refractory laryngeal sensory symptoms, supraglottic botulinum toxin type A significantly improved Laryngeal Hypersensitivity Questionnaire, Reflux Symptom Index, and Cough Severity Index scores at a mean of 5.2 weeks, while Voice Handicap Index‐10 scores remained unchanged.
Daniel Novakovic +3 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Indira Garcia‐Cordero +12 more
wiley +1 more source
The Scientific World Journal, 2017 Gabapentin is a well-established anticonvulsant drug which is also effective for the treatment of neuropathic pain. Although the exact mechanism leading to relief of allodynia and hyperalgesia caused by neuropathy is not known, the blocking effect of ...
Vittorio Vellani, Chiara Giacomoni
doaj +1 more source