Results 111 to 120 of about 60,800 (288)

Treatment Continuation and Long‐Term Outcomes of Perampanel in Primary Orthostatic Tremor; A Cohort Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Background Primary orthostatic tremor (POT) is a rare hyperkinetic movement disorder with limited and largely ineffective treatment options. Perampanel has been suggested as a therapy, but has so far only been investigated in small studies with short duration.
Wietske A. Babeliowsky   +4 more
wiley   +1 more source

Protein Kinase A–Dependence of the Supraspinally Mediated Analgesic Effects of Gabapentin on Thermal and Mechanical Hypersensitivity

open access: yesJournal of Pharmacological Sciences, 2009
.: We have recently shown that gabapentin generates protein kinase A (PKA)-dependent presynaptic inhibition of GABAergic synaptic transmission in locus coeruleus (LC) neurons only under neuropathic states.
Keiko Takasu   +3 more
doaj   +1 more source

Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]

open access: yes, 2003
Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
core   +1 more source

Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]

open access: yes, 2017
Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core   +1 more source

Quality of Life in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare disorder of the nervous system that detrimentally influences health‐related quality of life (HRQoL). Evidence regarding factors influencing HRQoL in CIDP is scarce.
Tobias C. Blum   +7 more
wiley   +1 more source

Gabapentin Inhibits Protein Kinase C Epsilon Translocation in Cultured Sensory Neurons with Additive Effects When Coapplied with Paracetamol (Acetaminophen)

open access: yesThe Scientific World Journal, 2017
Gabapentin is a well-established anticonvulsant drug which is also effective for the treatment of neuropathic pain. Although the exact mechanism leading to relief of allodynia and hyperalgesia caused by neuropathy is not known, the blocking effect of ...
Vittorio Vellani, Chiara Giacomoni
doaj   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman   +5 more
wiley   +1 more source

Gabapentin misuse [PDF]

open access: yesCanadian Medical Association Journal, 2019
Robin, Lennox, Dee, Mangin
openaire   +2 more sources

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

open access: yesPM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen   +7 more
wiley   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

open access: yesPM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy   +3 more
wiley   +1 more source

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