Results 21 to 30 of about 40,857 (285)

Protective Effect of Gabapentin on N-methyl-D-aspartate–Induced Excitotoxicity in Rat Hippocampal CA1 Neurons

Journal of Pharmacological Sciences, 2009
Gabapentin was developed as an anticonvulsant, but has also been used to alleviate hyperalgesia in neuropathic pain. In this study, the protective effect of gabapentin against N-methyl-D-aspartate (NMDA)-induced excitotoxicity in rat hippocampal CA1 ...
Young-Sick Kim, Hyun-Kyung Chang, Jin-Woo Lee, Yun-Hee Sung, Sung-Eun Kim, Mal-Soon Shin, Jae-Woo Yi, Je-Hoon Park, Hong Kim, Chang-Ju Kim   +9 more
doaj   +1 more source

Tri-partite complex for axonal transport drug delivery achieves pharmacological effect. [PDF]

, 2010
BACKGROUND: Targeted delivery of pharmaceutical agents into selected populations of CNS (Central Nervous System) neurons is an extremely compelling goal.
Sokoloff Alan J, Miri D Rabinowitz, Munglani, Raj, Filler, Aaron G, Filler, A.G, Munglani, R, Chris Abell, Rabinowitz, Miri D, Terrence W Deacon, Andrew ML Lever, Deacon Terrence W, Munglani Raj, Mark Bacon, Sokoloff, Alan J, Franklyn A Howe, Deacon, T.W, Whiteside, Garth T, Bacon, Mark, Howe, F.A, Abell, Chris, Sokoloff, AJ, Griffiths, J.R, Filler Aaron G, Lever, Andrew ML, Howe, FA, Alan J Sokoloff, Martyn Frederickson, Bell B Anthony, Bell, B.A, Bacon, M, Frederickson Martyn, Garth T Whiteside, Griffiths, John R, Abell, C, Aaron G Filler, B Anthony Bell, Griffiths John R, Rabinowitz Miri D, Bacon Mark, Bell, B Anthony, Lever, A.M.L, Frederickson, Martyn, Filler, AG, Abell Chris, Sokoloff, A.J, Frederickson, M, John R Griffiths, Lever Andrew ML, Whiteside Garth T, Deacon, Terrence W, Bell, BA, Whiteside, GT, Griffiths, JR, Rabinowitz, MD, Deacon, TW, Lever, AM, Whiteside, G.T, Howe Franklyn A, Howe, Franklyn A, Raj Munglani, Rabinowitz, M.D   +60 more
core   +2 more sources

Effects of pregabalin and gabapentin on postoperative pain and opioid consumption after laparoscopic cholecystectomy [PDF]

Korean Journal of Anesthesiology, 2017
BackgroundGabapentin and pregabalin are antiepileptic drugs that are also used for chronic pain treatment. This study evaluated the effects of pregabalin and gabapentin on postoperative pain in patients undergoing laparoscopic cholecystectomy.MethodsA ...
Mohammad Eidy, Mohammad Reza Fazel, Hossein Abdolrahimzadeh, Ali Reza Moravveji, Ebrahim Kochaki, Mahdi Mohammadzadeh   +5 more
doaj   +1 more source

Anticonvulsants in the treatment of aggression in the demented elderly : an update [PDF]

, 2009
Introduction Complex psychopathological and behavioral symptoms, such as delusions and aggression against care providers, are often the primary cause of acute hospital admissions of elderly patients to emergency units and psychiatric departments.
Ana Gonzalez-Pinto, Francesc Colom, Hampel, Harald, Colom, Francesc, 1971-, Johannes Pantel, Heinz Grunze, Amann, Benedikt L., Naber, Dieter, Gonzalez-Pinto, Ana, Pantel, Johannes, Eduard Vieta, Colom, Francesc, Vieta, Eduard, Harald Hampel, Amann, Benedikt, Dieter Naber, Grunze, Heinz, Vieta i Pascual, Eduard, 1963-, Benedikt Amann   +18 more
core   +1 more source

Gabapentin in Burns [PDF]

Archives of Trauma Research, 2014
Dear Editor, I read with interest the article entitled Effect of Gabapentin on Morphine Consumption and Pain after Surgical Debridement of Burn Wounds: A Double-Blind Randomized Clinical Trial Study and was impressed by the scientific rigor and level of detailed observation. This is especially admirable in a study performed at the front line of burn
openaire   +2 more sources

Comparative Effectiveness and Safety of Original Gabapentin and Generic Gabapentin in Treating Patients with Neuropathic Pain at Siriraj Hospital, Bangkok, Thailand

Siriraj Medical Journal, 2020
Background: Neuropathic pain (NP) develops as a consequence of a lesion or disease affecting the somatosensory system. Patients with severe NP usually suffer from pain and may need many treatment options.
Rungsan Chaisewikul, Ratikorn Saejong, Sasima Tongsai, Visanu Thamlikitkul   +3 more
doaj  

Gabapentin adjunctive to risperidone or olanzapine in partially responsive schizophrenia: an open-label pilot study [PDF]

, 2010
Adel GabrielDepartments of Psychiatry and Community Health Sciences, University of Calgary, Alberta, CanadaBackground: There is a great need in the treatment of schizophrenia for a drug, or drug ­combinations, to improve clinical response with ...
Adel Gabriel, Gabriel, Adel A.R.
core   +2 more sources

More Drug Monitoring and Less CT Scans of the Brain: Gabapentin Overdose in Two Peritoneal Dialysis Patients

Case Reports in Nephrology and Dialysis, 2022
In parallel with the decline of renal excretory function, drug dosing of many drugs becomes more challenging. Finding the right dose is even more difficult if kidney replacement therapy is instituted.
Kijanosh Lehmann, Sara Diab, Torsten M. Meyer, Jan T. Kielstein, Gabriele Eden   +4 more
doaj   +1 more source

Gabapentin prevalence: clinical and forensic experience in St. Louis, Missouri, USA

Forensic Sciences Research, 2021
Gabapentin (Neurontin) is an anti-epileptic drug that has had wide off-label prescription use since market release due to presumed negligible abuse potential.
Sarah B. Riley, Kelsie Garbutt, Chelsea Crow, T. Scott Isbell, Anthony J. Scalzo   +4 more
doaj   +1 more source

Gabapentin for Acute Postoperative Pain Control in Total Abdominal Hysterectomy: A randomized controlled trial

Thai Journal of Obstetrics and Gynaecology, 2021
Objectives: To evaluate the effect of gabapentin 300 mg in relieving acute postoperative pain in patients undergoing total abdominal hysterectomy at Chonburi Hospital. Materials and Methods: A double-blind, randomized, controlled
Hathaipat Sukjariangporn, Sittichoke Mahasukontachat   +1 more
doaj   +1 more source