Journal of Pharmacological Sciences, 2009 Gabapentin was developed as an anticonvulsant, but has also been used to alleviate hyperalgesia in neuropathic pain. In this study, the protective effect of gabapentin against N-methyl-D-aspartate (NMDA)-induced excitotoxicity in rat hippocampal CA1 ...
Young-Sick Kim +9 more
doaj +1 more source
Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol. [PDF]
, 2018 Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery.
Durazzo, Timothy C +3 more
core +2 more sources
Exploring the baseline knowledge and experience of healthcare professionals in the United Kingdom on Novel Psychoactive Substances [PDF]
, 2020 Submitted 28 january 2020. Reviwers' comments received 11 February 2020. Accepted 26 February 2020. Published 2 March 2020.Objective: This survey aimed to explore knowledge and experience on novel psychoactive substances (NPS) of healthcare professionals
Bancroft, Angus +9 more
core +3 more sources
Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]
, 2013 Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert +5 more
core +4 more sources
Managing the symptoms of neuropathic pain: An exploration of patients' experiences [PDF]
, 2007 The debilitating effects of chronic neuropathic pain on everyday life are considerable but little is known about how individual sufferers manage these effects.
Bennett +25 more
core +1 more source
Siriraj Medical Journal, 2020 Background: Neuropathic pain (NP) develops as a consequence of a lesion or disease affecting the somatosensory system. Patients with severe NP usually suffer from pain and may need many treatment options.
Rungsan Chaisewikul +3 more
doaj
Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]
, 2008 FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico +8 more
core +1 more source
Gabapentin prevalence: clinical and forensic experience in St. Louis, Missouri, USA
Forensic Sciences Research, 2021 Gabapentin (Neurontin) is an anti-epileptic drug that has had wide off-label prescription use since market release due to presumed negligible abuse potential.
Sarah B. Riley +4 more
doaj +1 more source
Case Reports in Nephrology and Dialysis, 2022 In parallel with the decline of renal excretory function, drug dosing of many drugs becomes more challenging. Finding the right dose is even more difficult if kidney replacement therapy is instituted.
Kijanosh Lehmann +4 more
doaj +1 more source
Gabapentin for pain management after osmotic dilator insertion and prior to dilation and evacuation: A randomized controlled trial. [PDF]
, 2020 ObjectiveTo evaluate if gabapentin 600 mg reduces pain after osmotic dilator placement the day before a dilation and evacuation (D&E) procedure.Study designWe conducted a double-blind, placebo-controlled, randomized (stratified by vaginal parity ...
Chen, Melissa J +5 more
core +3 more sources