Results 41 to 50 of about 35,480 (291)

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Akt2 inhibition alleviates temporomandibular joint osteoarthritis by preventing subchondral bone loss

Arthritis Research & Therapy
Background This study aimed to investigate the role and mechanism of the Akt2 pathway in different stages of anterior disc displacement (ADD)-induced temporomandibular joint osteoarthritis (TMJOA).
Shi-Yang Feng, Meng-Nan Cao, Chen-Chen Gao, Yi-Xin Li, Jie Lei, Kai-Yuan Fu   +5 more
doaj   +1 more source

Effect of standardized training in combination with masseter sensitization on corticomotor excitability in bruxer and control individuals: a proof of concept study

Scientific Reports, 2022
Recently, it has been proposed that bruxism could represent an overlearned behavior due to the absence of corticomotor plasticity following a relevant tooth-clenching task (TCT).
Noéli Boscato, Fernando G. Exposto, Yuri M. Costa, Peter Svensson   +3 more
doaj   +1 more source

Subtyping somatic tinnitus: a cross-sectional UK cohort study of demographic, clinical and audiological characteristics [PDF]

, 2015
Somatic tinnitus is the ability to modulate the psychoacoustic features of tinnitus by somatic manoeuvres. The condition is still not fully understood and further identification of this subtype is essential, particularly for the purpose of establishing ...
Hall, Deborah A, Hoare, Derek J, Vanneste, Sven, Vella, Claire, Ward, Jamie   +4 more
core   +3 more sources

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source

Analgesic potential of different available commercial brands of botulinum neurotoxin-A in formalin-induced orofacial pain in mice

Toxicon: X, 2021
The use of botulinum neurotoxin-A (BoNT-A) is an alternative for the management of orofacial pain disorders. Although only Botox has labeled, there are other commercial brands available for use, among them: Dysport, Botulift, Prosigne, and Xeomin.
Thays Crosara Abrahão Cunha, Ana Claudia Gontijo Couto, Eduardo Januzzi, Rafael Tardin Rosa Ferraz Gonçalves, Graziella Silva, Cassia Regina Silva   +5 more
doaj   +1 more source

Parameter estimation in Cox models with missing failure indicators and the OPPERA study [PDF]

, 2015
In a prospective cohort study, examining all participants for incidence of the condition of interest may be prohibitively expensive. For example, the "gold standard" for diagnosing temporomandibular disorder (TMD) is a physical examination by a trained ...
Bair, Bender, Chen, Cook, Dodd, Dworkin, Efron, Fillingim, Gijbels, Greenspan, Little, Magaret, Magder, Maixner, Maixner, McKeague, Ohrbach, Rubin, Rubin, Slade, Slade, Smith, Subramanian   +22 more
core   +3 more sources

Double‐vestibular incision subperiosteal tunnel access (double‐VISTA) with connective tissue graft for treating multiple gingival recessions: 2‐year follow‐up

Clinical Advances in Periodontics, EarlyView.
Abstract Background Gingival recession has a multifactorial etiology, involving various predisposing and precipitating factors. Non‐carious cervical lesions (NCCLs) are often associated with gingival recession and pose challenges due to their complex pathodynamics.
Guo‐Hao Lin
wiley   +1 more source

Assessment of symptoms of temporomandibular dysfunction in patients undergoing orthodontic treatment using occlusal lift

BrJP
BACKGROUND AND OBJECTIVES: The use of orthodontic appliances is constantly associated with symptoms of temporomandibular disorder (TMD). In this sense, the present study aimed to investigate the development of TMD symptoms in patients undergoing ...
Isabella Avelar Santos, Gracia Lopes Costa, Rodrigo Bernardes Pereira, Thiago Bezerra Leite, António Sérgio Guimarães, Luciane Lacerda Franco Rocha Rodrigues   +5 more
doaj   +1 more source

Clinical factors affecting depression in patients with painful temporomandibular disorders during the COVID-19 pandemic

Scientific Reports, 2022
Temporomandibular disorders (TMD) are a multifactorial condition associated with both physical and psychological factors. Stress has been known to trigger or worsens TMD.
Yeon-Hee Lee, Q-Schick Auh
doaj   +1 more source