Results 161 to 170 of about 337,580 (303)

In Situ Gels for Nasal Delivery: Formulation, Characterization and Applications

Macromolecular Materials and Engineering, EarlyView.
Drug delivery through the nasal route offers many advantages, but is hampered by a number of challenges, such as the short drug retention time caused by mucociliary clearance. In situ forming gels, which undergo a sol‐to‐gel transition with specific triggers at the site of action, present real opportunities in this field.
Li Qian, Michael T. Cook, Cécile A. Dreiss   +2 more
wiley   +1 more source

Oral and oropharyngeal mucosal lesions: clinical-epidemiological study of patients attended at a reference center for infectious diseases

Brazilian Journal of Otorhinolaryngology
Objective: To determine the prevalence, epidemiological profile, and clinical characteristics of Oral or Oropharyngeal Mucosal Lesions (OOPML) in patients attended at the Otorhinolaryngology Service of the Evandro Chagas National Institute of Infectious ...
Clarissa Souza Mota Reis, João Gustavo Corrêa Reis, Fátima Conceição-Silva, Cláudia Maria Valete   +3 more
doaj  

Enhancing accuracy in proton therapy: The impact of geometric uncertainty models in head and neck cancer treatment

Medical Physics, EarlyView.
Abstract Background Anatomical changes present a major source of uncertainty in head and neck (H&N) cancer treatment. Accurate modeling of these changes is important for enhancing treatment precision and supporting better outcomes. Purpose The purpose of this study is to assess different anatomical uncertainty modeling methods in robust optimization ...
Ying Zhang, Mark Ka Heng Chan
wiley   +1 more source

Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition

Nano Select, EarlyView.
Nanoplastic hydrophobicity drives adverse effects in the lung. Single intratracheal administration of poly(vinyl acetate‐co‐alcohol) nanoplastics with varying surface hydrophobicity shows that the more hydrophobic nanoplastics increase prevalence of coarsely vacuolated alveolar macrophages, induce transient respiratory inflammation and mild collagen ...
Anna Babin Morgan, Yanira Riffo‐Vasquez, Aateka Bodhaniya, Stuart A. Jones, Ben Forbes, Kavitha Sunassee, Rafael T. M. de Rosales, Stephanie Wright, Clive Page, Lea Ann Dailey   +9 more
wiley   +1 more source

Functional Outcomes of Free Flap Reconstruction After TORS in Early‐Stage HPV‐Positive Oropharyngeal Cancer

Otolaryngology–Head and Neck Surgery, EarlyView.
ABSTRACT Objective In the unique clinical context of a retropharyngeal carotid artery (RPC), free flap reconstruction (FFR) may be used for small pathologic tumor (pT)1‐2 human papillomavirus (HPV)+ oropharyngeal squamous cell carcinoma (OPSCC) tumors to provide vessel coverage, providing a unique case‐control study model.
Praneet C. Kaki, Neel R. Sangal, Doreen Lam, Ryan M. Carey, Karthik Rajasekaran, Ara Chalian, Robert M. Brody, Gregory S. Weinstein, Steven B. Cannady   +8 more
wiley   +1 more source

Online Discourse and Trends Surrounding HPV Vaccination for Head and Neck Cancer Prevention

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective In 2020, the Food and Drug Administration (FDA) approved Merck's GARDASIL 9 for prevention of certain human papillomavirus (HPV)‐related head and neck cancer. This study characterizes the sentiment and themes of HPV vaccination online discourse surrounding the 2020 FDA recommendation. Study Design Retrospective cohort.
Andrew Meci, Christopher C. Tseng, Zackary Jensen, Neerav Goyal   +3 more
wiley   +1 more source

Impact of the COVID-19 Pandemic on Delay in Treatment Initiation for Oral Cavity and Oropharyngeal Cancer in Brazil

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To analyze the impact of the COVID-19 pandemic on the interval between diagnosis and initiation of treatment for oral cavity and oropharyngeal cancer in Brazil.
Israel Monteiro Araújo, Márcio Vinícius Campos Borges, Luís Gustavo Souza Santos, Jessilene Ribeiro Rocha, Érika Martins Pereira, Vandilson Pinheiro Rodrigues   +5 more
doaj  

Can Manual Therapy Alter Muscle Stiffness in Patients With Spinal Accessory Nerve Injury?

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Shoulder and neck dysfunctions resulting from spinal accessory nerve injury impair quality of life. This study aims to investigate the effects of manual therapy in combination with standard physiotherapy on the mechanical properties of muscle, neck and shoulder function, pain, and quality of life in head and neck cancer patients ...
Ferhat Simsek, Baha Naci, Meltem Bozaci Kilicoglu, Zeynep Alkan, Osman Melih Topcuoglu, Aysegul Gormez, Gunter Hafiz, Ali Fethi Okyar   +7 more
wiley   +1 more source

The Classification of Axial Deformity in Patients with Basilar Invagination

Orthopaedic Surgery, Volume 14, Issue 12, Page 3150-3158, December 2022., 2022
Axis deformities were divided into four types. Type I: the axis is basically normal. Type II: axis lateral mass is dysplasia. Type III: axis pedicle is dysplasia. Type IV: axis pedicle and lateral mass are all dysplasia. The axis variation rate of patients with basilar invagination was as high as 42.4%, of which type IV was the most common.
Qiting He, Jiankang Cao, Huichao Tian, Bin Chen, Xincheng Fan, Shaoyi Wang, Yunpeng Zhao, Jianlu Wei, Lin Nie, Xin Pan, Lei Cheng   +10 more
wiley   +1 more source

Altered Bacteria Abundance Is Associated With Outcomes in Head and Neck Squamous Cell Carcinoma

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To determine if microbiome differences exist in head and neck squamous cell carcinoma (HNSCC) based on high‐risk pathologic features, smoking, and outcomes using The Cancer Microbiome Atlas (TCMA). Study Design Database study. Setting Database review.
Delaney H. Sheehan, Kesava Asam, Nicolaus D. Knight, Juhi J. Patel, James A. Stewart, Patrick A. Molina, Nengjun Yi, Chi T. Viet, Brad Aouizerat, Natalie Silver, Bharat Panuganti, Carissa M. Thomas   +11 more
wiley   +1 more source