Results 161 to 170 of about 139,309 (247)

Myofibroblast‐Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer

Cancer Science, EarlyView.
Compared with PT‐CAFs, LN‐CAFs exhibited a myofibroblast‐like phenotype, enhanced tumor stemness‐promoting activity, and fibrosis‐, EMT‐, and hypoxia‐related transcriptomic signatures. LN‐CAF‐related gene signatures were independently associated with poor prognosis in head and neck squamous cell carcinoma.
Hiroyuki Hagiwara, Hideyuki Takahashi, Reika Kawabata‐Iwakawa, Miho Uchida, Hiroe Tada, Toshiyuki Matsuyama, Masaomi Motegi, Yuichi Tomidokoro, Kazuaki Chikamatsu   +8 more
wiley   +1 more source

da Vinci Single‐Port Transoral Robotic Surgery in European Practice: Early Outcomes and Comparison With Transoral Laser Microsurgery

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives To report early outcomes following implementation of a da Vinci Single‐Port transoral robotic surgery (SP‐TORS) programme in the United Kingdom. To provide contextual benchmarking, outcomes were compared with a historical institutional cohort treated using transoral laser microsurgery (TLM). Design Retrospective institutional series
Matthew E. Ryan, Matthew Zammit, Kristijonas Milinis, Omar Ahmed, Rupali Sawant, Ava Gubbay, Somer Scott‐Clarkson, Harishanker Jeyarajan, Terry M. Jones, Mark Wilkie, Katharine Davies, Christopher Loh, Jason C. Fleming   +12 more
wiley   +1 more source

Concordance of p16 status between US-guided core needle biopsy and surgical specimens in oropharyngeal squamous cell carcinoma: A diagnostic accuracy study. [PDF]

Medicine (Baltimore)
Lee D, Choi YJ, Song JS, Lee YS, Chung SR, Baek JH, Lee JH.   +6 more
europepmc   +1 more source

Cold plasma treatment for oral lichen planus: a retrospective case collection and proposal of a new clinical score

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer, Hans‐Robert Metelmann, Mohamed Falougy, Wolfram Kaduk, Lasse Kremer, Georg Daeschlein   +5 more
wiley   +1 more source

Potential Years of Life Lost Due to Lip, Oral and Oropharyngeal Cancer in Brazil: Estimates and Forecasting. [PDF]

Int Dent J
Salvi LC, Costa FDS, Collares KF, D'avilla OP, Pinto LF, Demarco FF, Vasconcelos ACU, Chisini LA.   +7 more
europepmc   +1 more source

Prevalence of Oral Mucosal Lesions in Finnish Adults—Findings From the Healthy Finland Survey

Gerodontology, EarlyView.
ABSTRACT Objectives Oral mucosal lesions (OMLs) are abnormal findings of the oral mucosa. OMLs can be a localized disease due to trauma or infections, a manifestation of systemic or dermatological disease, or a sign of neoplasia. The aim of this study was to assess the prevalence of OMLs among Finnish adults.
Mirjami J. Rintala, Heidi E. Tuominen, Hanna K. Laine, Anna L. Suominen, Ulla Harjunmaa, Jaana Rautava   +5 more
wiley   +1 more source

A multicenter randomized phase III trial of weekly cisplatin chemoradiotherapy versus radiotherapy in elderly patients with head and neck squamous cell carcinoma unfit for high-dose cisplatin: JCOG2405 (ELDER-WEEKLY). [PDF]

Jpn J Clin Oncol
Kawabata K, Yasuda K, Nakamura S, Honma Y, Suzuki R, Ueda Y, Saito S, Matsuura K, Hanai N, Nakamura N, Mizusawa J, Sasaki K, Fukuda H, Mizowaki T, Kiyota N, Head and Neck Cancer Study Group and the Radiation Therapy Study Group of the Japan Clinical Oncology Group.   +15 more
europepmc   +1 more source

Distinct Rb expression pattern in HPV‐associated neuroendocrine carcinomas of the uterine cervix

Histopathology, EarlyView.
Most uterine cervical neuroendocrine carcinoma (UCNEC) cases are HPV‐associated and are characterized by partial loss of Rb, p16 overexpression, and cyclin D1 negativity. A minority of UCNECs exhibit a distinct pattern, characterized by HPV negativity, retained Rb expression, focal p16 expression and cyclin D1 positivity.
Nobuko Yasutake, Misato Komamizu, Takeshi Iwasaki, Ryosuke Kuga, Tomomi Manako, Mikiko Hashisako, Rina Jiromaru, Tomoko Sho, Norihito Yuge, Kenzo Sonoda, Hideaki Yahata, Yoshinao Oda, Hidetaka Yamamoto   +12 more
wiley   +1 more source

Small Cell Neuroendocrine Carcinoma of the Oropharynx Harbouring Oncogenic HPV-Infection

Small cell carcinoma/neuroendocrine carcinoma (SCNEC) of the oropharynx is uncommon. Recently, an association has been reported between oropharyngeal SCNEC and high-risk human papillomavirus (HPV) infection. While HPV infection confers a better prognosis
Kelly C, Bates T, Robinson M, Iqbal MS, McQueen A   +4 more
core   +1 more source

Italian regional data and oropharyngeal adverse events to drugs and vaccines: insights from a 3-year spontaneous reporting (2022-2024). [PDF]

Pharmacol Rep
Sportiello L, Gaio M, Zinzi A, La Mantia G, Panzarella V, Colella G, Marra PM, Sottosanti L, Potenza S, Oteri G, Coppini M, Seminara G, Mauceri R, Morreale I, Fusco V, Campisi G, Capuano A.   +16 more
europepmc   +1 more source