Results 131 to 140 of about 4,808 (171)

Observations on the thermostability of orosomucoid

Biochemical and Biophysical Research Communications, 1981
Summary Orosomucoid is shown to have no special resistance to thermal denaturation, contrary to previous thought. Earlier conclusions probably arose from the great solubility of the molecule, even at elevated temperature. Under otherwise physiological conditions, orosomucoid begins denaturing at ∼46°C with a T m of 62°C.
H B, Halsall, T L, Kirley
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Microheterogeneity of orosomucoid in pathological conditions

ELECTROPHORESIS, 1989
AbstractStudies of orosomucoid (α1‐acid glycoprotein) in human serum have revealed that orosomucoid is a mixture of molecules with differences in the glycan chains. This microheterogeneity has been studied using crossed affinoimmuno‐electrophoresis with the lectin concanavalin A which binds to biantennary glycans.
J E, Hansen, T C, Bøg-Hansen, B, Pedersen, K, Neland   +3 more
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Orosomucoid System: 17 Additional Orosomucoid Variants and Proposal for a New Nomenclature

Vox Sanguinis, 1993
AbstractThere are two forms of orosomucoid (ORM) in the sera of most individuals. They are encoded by two separate but closely linked loci, ORM1 and ORM2. A number of variants have been identified in various populations. Duplication and nonexpression are also observed in some populations. Thus, the ORM system is very complicated and its nomenclature is
I, Yuasa, S, Weidinger, K, Umetsu, K, Suenaga, G, Ishimoto, B C, Eap, J C, Duche, P, Baumann   +7 more
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Comparison of Bovine and Human Orosomucoids

Nature, 1962
THE existence of acidic glycoproteins in human1–3 and bovine4,5 sera has been well established. A bovine M-2 glycoprotein has been isolated in an apparently pure state as described by us earlier5, and bovine orosomucoid has been purified by Weimer and Winzler4.
A, BEZKOROVAINY, D G, DOHERTY
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Some immunochemical studies on orosomucoid

Clinica Chimica Acta, 1963
Abstract An acidic glycoprotein has been isolated from nephrotic urine by means of DEAE cellulose chromatography. The homogeneity of the glycoprotein was investigated and an antiserum raised to it in rabbits. Periodate oxidation of the glycoprotein was carried out in order to assist in determining the antigenic moiety of the molecule.
S A, BARKER, P H, WHITEHEAD
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Studies on Orosomucoid in Normal Infants and Children

Scandinavian Journal of Clinical and Laboratory Investigation, 1962
AbstractThe orosomucoid content of serum has been determined in healthy infants and children. Analyses of haptoglobin and of electrophoretic protein fractions have also been made.The mean umbilical cord serum level of orosomucoid was significantly lower than the level in the maternal serum. Apart from a transient increase during the first week of life,
L, SUNDBLAD, K, WALDTON, M, WALLIN-NILSSON   +2 more
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Serum orosomucoid concentration in newborn infants

European Journal of Pediatrics, 1981
Serum orosomucoid concentration was measured by laser nephelometry in 1970 serum samples collected from 1170 full term and preterm infants. The determinations were carried out in 1 h. Reference values are given: they show that the low levels at birth are influenced by gestational age.
L, Sann, J, Bienvenu, C, Lahet, P, Divry, J, Cotte, M, Bethenod   +5 more
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Pro-angiogenic properties of orosomucoid (ORM)

Experimental Cell Research, 2009
The acute phase protein orosomucoid (ORM), also known as alpha1-acid glycoprotein (AGP), is found to be increased in infection, inflammation and cancer. Recently, we demonstrated that ORM is produced by endothelial cells and detectable in urine samples of patients with bladder cancer.
Ster, Irmak, Leticia, Oliveira-Ferrer, Bernhard B, Singer, Süleyman, Ergün, Derya, Tilki   +4 more
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Inhibition of viral hemagglutination by aggregated orosomucoid

Archives of Biochemistry and Biophysics, 1968
Abstract The aggregation of orosomucoid by heating at 80 °, and its resultant capacity to inhibit viral hemagglutination by PR8 influenza virus has been studied. Heating orosomucoid in unbuffered saline resulted in a polydisperse aggregate. Fractionation of such preparations on Sephadex G-200 resulted in a separation into three components.
P H, Whitehead, R J, Winzler
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Studies on Orosomucoid and Haptoglobin in Rheumatoid Arthritis

Scandinavian Journal of Rheumatology, 1961
ResumeLa presence d'orosomucoide, d'haptoglobine, de glycoproteides PCA solubles et d'acide sialique a ete determinee dans le serum et dans le fluide synovial en cas de polyarthrite chronique evolutive. Dans cette maladie l'accroissement de la teneur en acide sialique dans le serum est du dans une large mesure a un accroissement d'orosomucoide et d ...
E, NETTELBLADT, L, SUNDBLAD
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