Results 21 to 30 of about 124,112 (267)
Remote homology and the functions of metagenomic dark matter
Frontiers in Genetics, 2015 Predicted open reading frames (ORFs) that lack detectable homology to known proteins are termed ORFans. Despite their prevalence in metagenomes, the extent to which ORFans encode real proteins, the degree to which they can be annotated, and their ...
Briallen eLobb +3 more
doaj +1 more source
Frontiers in Pharmacology, 2015 Orphan G protein-coupled receptors (GPCRs) represent a largely untapped resource for the treatment of a variety of diseases, despite sophisticated advances in drug discovery.
Nicola J Smith, Nicola J Smith
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Tillfällighetsmodrande och föräldralösa barn i amerikanska post-9/11-romaner
Kvinder, Køn & Forskning, 2015 This article explores how ideas about national identity are staged and critiqued through representations of family relations in two American post-9/11 novels, focusing more specifically on mothering and the orphan child.
Helena Wahlström Henriksson
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Preliminary Cross-Sectional Screening for the Assessment of Macronutrient Consumption and Body Mass Index in Orphans Aged 7 to 15 Years in Amman, Jordan [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2018 The aim of this study was to screen for malnutrition by evaluating macronutrient intake and calculating the ratio of body mass index (BMI) to age of orphans in 7 selected governmental orphanages in Amman, Jordan.
Hadeel Ghazzawi
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Üsküdar Şer’iyye Sicillerine Göre Eytam Mallarının Finansal Kullanımı (1850-1856)
Kocatepe İslami İlimler Dergisi, 2023 Osmanlı Devleti’ndeki finansal sistem, İslam hukuku çerçevesinde şekillenirken, özellikle klasik dönemde yerel düzeyde kalmış, Tanzimat Fermanı’nın ilanından sonra ise merkezî bir hal kazanarak kurumsallaşma sürecine girmiştir.
Necla Kızıldağ, Mustafa Güler
doaj +1 more source
Journal of the International AIDS Society, 2014 Introduction Every year, approximately 260,000 children are infected with HIV in low‐ and middle‐income countries. The timely initiation and high level of maintenance of antiretroviral therapy (ART) are crucial to reducing the suffering of HIV‐positive ...
Kimiyo Kikuchi +9 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Community-based Psychosocial Support for Orphan and Vulnerable Children living in an Orphanage
Journal of Innovation and Applied Technology, 2023 Orphan and children living in orphanages are a high-risk group vulnerable to psychosocial problems. Individual who lived in this community are not only orphans but also children and people from low-income families.
Ridhoyanti Hidayah +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source