Results 111 to 120 of about 6,140 (302)

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

open access: yesEpilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini   +15 more
wiley   +1 more source

Deformations in Economic Consciousness of Children Raised in Orphanages

open access: yes, 2015
The aim of the present work was to study the deformations of economic consciousness in adolescents raised in orphanages. It was found that, due to deprivation of economic and social experience, children who were raised in orphanages have a high risk of ...
Irina Valerievna Golubeva   +1 more
core   +1 more source

Effectiveness and tolerability of fenfluramine in pediatric and adult patients with developmental and epileptic encephalopathies: A multicenter, retrospective, real‐world clinical‐practice study

open access: yesEpilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by drug‐resistant seizures and developmental slowing/regression. We examined the efficacy and tolerability of fenfluramine (FFA) in pediatric and adult patients with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS), and other DEEs.
Vicente Villanueva   +29 more
wiley   +1 more source

Psychiatric disorders among children living in orphanages - experience from Kashmir

open access: yes, 2011
IntroductionIn the conflict torn developing countries, where adoption and foster care are little practised, orphanages remain one of the few means of survival of inumerable orphans. Critical research, however, has potrayed orphanages as a breeding ground
Y. Rather
core   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Children from orphanages and their integration into the class group [PDF]

open access: yes, 2012
Annotation: The thesis name The children from orphanages and their integration into the class group is focused on taking the role of student by children from orphanages. The thesis is divided into a theoretical, methodological and practical part.
Pejclová, Simona
core  

Counselling Needs of Adolescents in Orphanages in Kebbi State, Nigeria

open access: yes, 2021
This study looked at the counselling needs of adolescent in orphanages. Descriptive survey method was used in this study. The target population of this study comprised of all adolescents in the orphanages in Kebbi State.
Adebayo David O.   +2 more
core  

Neurolathyrism in Sub‐Saharan Africa—Assessing the Neurotoxic Risks of Lathyrus sativus Amid Drought and Food Security Challenges

open access: yesFood Safety and Health, EarlyView.
Representation of grass pea consumption in drought‐stricken sub‐Saharan Africa sustains nutrition, but excess β‐ODAP exposure due to multiple reasons triggers neurolathyrism, a progressive neurotoxic disorder. ABSTRACT Neurolathyrism is a progressive motor neuron disease due to the consumption of Lathyrus sativus (grass pea) over long periods.
Biruk Demisse Ayalew   +12 more
wiley   +1 more source

The Psychomotor Development Children from Prague Schools and Orphanages [PDF]

open access: yes, 2015
Bibliographic Identification Name and surname of the author: Mgr. Jakub Holický Name of dissertation: The Psychomotor Development Children from Prague Schools and Orphanages Workplace: Department of Pedagogy, Psychology and Didactics of Physical ...
Holický, Jakub
core  

Orphanages and Health and Social Care for Children During the Great Patriotic War and Post-War Decade (1941–1956)

open access: yesВопросы современной педиатрии
This article presents the results of historical and medical study based on archival and literary sources. It demonstrates the state of orphanages and health and social care for children who were in hard times and socially dangerous situations during the ...
Stella A. Sher, Valery Yu. Albitskiy
doaj   +1 more source

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