Results 31 to 40 of about 6,140 (302)

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Role of Nonprofit Organizations and Volunteer Services in the Implementation of the National Strategy on Action for Children 2012–2017

open access: yesПсихологическая наука и образование, 2016
We analysed the role of socially oriented NGOs and volunteer services in the implementation of the objectives of National Strategy for Action on Children 2012–2017 and priority activities in the provision of services to vulnerable children and their ...
Semya G.V.,, Telitsyna A.Y.,
doaj   +1 more source

Cuerpos abandonados y rescatados. La educación física en los orfanatos españoles del siglo XIX [PDF]

open access: yesCabás, 2013
La sociedad decimonónica española promovió la institucionalización asistencial de los niños expósitos. Los orfanatos se convirtieron en centros de formación en los que se desarrolló un currículo oculto con el objeto de proteger la infancia desamparada,
Torrebadella-Flix, X.
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The origins of residential child care in Scotland

open access: yesScottish Journal of Residential Child Care, 2022
This paper describes the origins of residential care services for children and young people in Scotland. It focuses on the early history of orphanages, children's homes, industrial schools, and reformatory schools.
Andrew Kendrick
doaj   +1 more source

Impact of oral diseases on daily activities among 12- to 15-year-old institutionalized orphan and non-orphan children in Bengaluru city: A cross-sectional analytical study

open access: yesIndian Journal of Dental Research, 2020
Background and Objective: As parents are the primary decision-makers of child's health, a study was conducted to assess and compare the oral health status and impact of oral diseases on daily activities among 12- to 15-year-old institutionalized orphan ...
Varsha K Pavithran   +6 more
doaj   +1 more source

Providing the population of the Tatar ASSR with food on the eve and during the Great Patriotic war

open access: yesИсторическая этнология, 2022
Nutrition is a natural human need. The lack or absence of products affects all vital functions of the body, primarily maintaining health, working capacity, and childbearing.
Ilnara I. Khanipova   +1 more
doaj   +1 more source

A Pious Privilege: Printing for Hospitals and Orphanages across the Spanish Empire

open access: yes, 2023
By readdressing the printing privileges in case studies related to hospitals and orphanages between 1598 and 1837, decisive yet overlooked structural forces and strategies in the book trade come to light on the peninsula as well as in the overseas ...
Gehbald, Agnes
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

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