Results 51 to 60 of about 7,527 (257)

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Molluscum contagiosum and dental caries: A pertinent combination

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2009
Background: In recent decades, there has been a tremendous surge of interest in issues related to child health. The present study was carried out to reveal the DMFT/deft status of children in the age group of 1-12 years, residing in orphanages from Pune,
Dixit S, Chaudhary M, Singh A
doaj  

Assessment of facilities and best practices in orphanages in Benin City, south-south region, Nigeria [PDF]

open access: yes, 2017
Aim: Increasing number of orphans will adversely affect the existing facilities and best practices in orphanages if there are no plans to accommodate the anticipated increase in demands.
Nwaneri, D.U., Sadoh, A.E.
core   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum   +13 more
wiley   +1 more source

Versatility in the design of orphanages: analysis of the history of European models

open access: yesАрхитектон
The article examines the problem of designing orphanages in the context of modern challenges such as military conflicts, economic crises and natural disasters in many countries of the world.
Akeel Aya
doaj   +1 more source

Protection of motherhood and infancy in the first decade of Soviet government in the Tambov Region (1918-1928)

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2019
The social policy regarding motherhood and infancy, including the system of social protection of orphans in the Tambov Governorate in the first decade of Soviet government (1918-1928) was specially and comprehensively studied in the context of state ...
P. P. Shcherbinin
doaj   +1 more source

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas   +4 more
wiley   +1 more source

Understanding Arthrogryposis Multiplex Congenita (AMC) Across the Lifespan: An Integrative Review of the Adult AMC Registry's Contributions With Lived Experience Partnerships

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT This reflective essay explores how collaborative work between researchers and adults living with Arthrogryposis Multiplex Congenita (AMC) has deepened and broadened our understanding of what it means to live with this rare condition. By intentionally integrating the lived experiences of individuals with AMC into research processes, the ...
Bonita J. Sawatzky   +3 more
wiley   +1 more source

Counselling Needs of Adolescents in Orphanages in Kebbi State, Nigeria [PDF]

open access: yes, 2021
This study looked at the counselling needs of adolescent in orphanages. Descriptive survey method was used in this study. The target population of this study comprised of all adolescents in the orphanages in Kebbi State.
Adebayo David O.   +2 more
core   +1 more source

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