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Ortho-aminobenzoic acid as a fluorescent probe for the interaction between peptides and micelles

Biophysical Chemistry, 1998
Ortho-aminobenzoic acid (o-Abz) has been used as a fluorescent probe in internally quenched fluorescent peptides for continuous protease assays. We investigated the fluorescent properties of the probe in order to verify if it can be used to monitor the interaction of peptides with micelles.
R F, Turchiello   +4 more
openaire   +2 more sources

Fluorescent properties of amino acids labeled withortho-aminobenzoic acid

Biospectroscopy, 1998
ortho-Aminobenzoic acid (Abz) has been used as a convenient fluorescent donor group in internally quenched fluorescent peptides, which are employed as substrates for several proteolytic enzymes. As Abz is usually bound to the N-amino terminal of these peptides, it is of interest to investigate the Abz group fluorescent properties bound to different ...
Ito, A.S.   +5 more
openaire   +2 more sources

The effect of solvent relaxation processes on the fluorescence spectra of ortho-aminobenzoate anesthetics

Journal of Photochemistry and Photobiology A: Chemistry, 1988
Abstract This paper reports on the effect of solvent viscosity on the emission spectra of a series of local anesthetic analogues containing the ortho -aminobenzoate (anthranilate) chromophore. The emission spectra of these compounds in glycerol undergo a blue shift with decreasing temperature in accordance with solvent relaxation.
W. Birmachu, J.K. Reed
openaire   +1 more source

Effect of hydrogen bond formation on the NMR properties of microhydrated ortho-aminobenzoic acid

Molecular Physics, 2012
The influence of the hydrogen bond formation on the nuclear magnetic resonance parameters has been investigated in the case of microhydrated ortho-aminobenzoic acid (o-Abz) in the gas-phase. DFT-B3LYP/aug-cc-pVDZ predicted 1H and 13C isotropic chemical shifts with respect to TMS of the isolated o-Abz are in reasonable agreement with available ...
Angsula Ghosh   +2 more
openaire   +1 more source

Synthesis, Spectroscopic Characterization and Antitumour Activity of Diorganotin(IV) Derivatives of N‐Substituted Ortho‐Aminobenzoic Acid

Bulletin des Sociétés Chimiques Belges, 1991
AbstractFour compounds of the type [(o‐RNH‐C6H4COO)(CH3CH2CH2CH2)2Sn]2O and [(o‐CH3NH‐C6H4COO)(CH3)2Sn]2O have been prepared, characterized by 1H, 13C, 119Sn NMR, and by Mössbauer and mass spectrometry. They have been tested in vitro against two human tumour cell lines, nl.
Meriem, Abdelkader   +6 more
openaire   +2 more sources

Intramolecular hydrogen bonding, a factor in benzoate-antibenzoate combination.

Molecular Pharmacology, 1969
In order for a substituted benzoate ion to combine most effectively with the receptor site of antibody to the p -azobenzoate group, it appears that the carboxylate group must be coplanar with the benzene ring.
T. Mao, A. Grossberg, D. Pressman
semanticscholar   +1 more source

The Reactions of Ortho Aminobenzoic Acids with Gold's Reagent: A Two Atom Lynch Pin Transformation

Synthetic Communications, 1984
Abstract A series of ortho aminobenzoic acids were treated with Gold's reagent. In each case a 4-hydroxyquinazoline was produced. The resulting transformation constitutes the use of Gold's reagent as a two atom lynch pin.
John T. Gupton   +2 more
openaire   +1 more source

ChemInform Abstract: Synthesis, Spectroscopic Characterization and Antitumor Activity of Diorganotin(IV) Derivatives of N‐Substituted ortho‐Aminobenzoic Acid.

ChemInform, 1991
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. MERIEM   +6 more
openaire   +1 more source

Saturated mimetics for ortho-substituted benzenes.

Angewandte Chemie, 2020
Saturated mimetics for ortho -disubstituted benzenes - bicyclo[2.1.1]hexanes, - were synthesized, characterized and validated. These cores were incorporated into bioactive compounds Valsartan, Boskalid and Fluxapyroxad instead of the benzene ring.
Aleksandr V. Denisenko   +4 more
semanticscholar   +1 more source

Effects of Microhydration on the Electronic Properties ofortho-Aminobenzoic Acid

The Journal of Physical Chemistry A, 2013
High-level density functional electronic structure calculations have been performed to analyze the effect of microsolvation with water on the electronic properties of ortho-aminobenzoic acid (o-Abz). The hydrogen-bonded interaction of the o-Abz molecule with one to three water molecules, o-Abz···(H2O)n (n = 1–3), has been considered in two different ...
Vanusa Bezerra, Pachêco   +1 more
openaire   +2 more sources

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