The Role of Orthobunyavirus Glycoprotein Gc in the Viral Life Cycle: From Viral Entry to Egress [PDF]
Orthobunyavirus refers to the virus members within the Genus Orthobunyavirus, which is the largest virus genus in the Family Peribunyaviridae and even Class Bunyaviricetes.
Han Gao+8 more
doaj +3 more sources
Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models. [PDF]
Reassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen+7 more
doaj +3 more sources
Orthobunyavirus Antibodies in Humans, Yucatan Peninsula, Mexico [PDF]
We performed a serologic investigation to determine whether orthobunyaviruses commonly infect humans in the Yucatan Peninsula of Mexico. Orthobunyavirus-specific antibodies were detected by plaque reduction neutralization test in 146 (18%) of 823 persons
Bradley J. Blitvich+6 more
doaj +5 more sources
The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture [PDF]
The Bunyavirales order is the largest group of negative-sense RNA viruses, containing many lethal human pathogens for which approved anti-infective measures are not available.
Francis R. Hopkins+7 more
doaj +5 more sources
Severe Sepsis Caused by California Serogroup Orthobunyavirus [PDF]
To the Editor: The California serogroup (CAL) of orthobunyaviruses, including Jamestown Canyon virus (JCV) and La Crosse virus (LACV), can cause neuroinvasive disease in humans (1–3). The epidemiology and clinical spectrum of LACV are well described (3), whereas less is known about JCV. JCV is distributed throughout temperate North America, and its
Daniel K. Rogstad+3 more
doaj +4 more sources
Fort Sherman Virus Infection in Human, Peru, 2020 [PDF]
Fort Sherman virus (FSV) was isolated in Panama in 1985 from a US soldier. We report a case of human FSV infection in a febrile patient from northern coastal Peru in 2020. FSV infections spanning ≈35 years and a distance of 2,000 km warrant diagnostics,
Edmilson F. de Oliveira-Filho+9 more
doaj +2 more sources
A mix-and-match reverse genetics system for evaluating genetic determinants of orthobunyavirus neurological disease. [PDF]
Miettinen HM, Abbott MJ, Evans AB.
europepmc +2 more sources
Oropouche Fever, Cuba, May 2024 [PDF]
Phylogenetic analyses showed that the virus responsible for a May 2024 Oropouche fever outbreak in Cuba was closely related to viruses from Brazil in 2023. Pools of Ceratopogonidae spp.
Ana Julia Benitez+17 more
doaj +2 more sources
<i>Oropouche orthobunyavirus</i> in Urban Mosquitoes: Vector Competence, Coinfection, and Immune System Activation in <i>Aedes aegypti</i>. [PDF]
de Mendonça SF+19 more
europepmc +2 more sources
Revisiting the Importance of Orthobunyaviruses for Animal Health: A Scoping Review of Livestock Disease, Diagnostic Tests, and Surveillance Strategies for the Simbu Serogroup [PDF]
Orthobunyaviruses (order Bunyavirales, family Peribunyaviridae) in the Simbu serogroup have been responsible for widespread epidemics of congenital disease in ruminants.
Tiffany W. O’Connor+4 more
doaj +2 more sources