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The Role of Orthobunyavirus Glycoprotein Gc in the Viral Life Cycle: From Viral Entry to Egress [PDF]

open access: goldMolecules
Orthobunyavirus refers to the virus members within the Genus Orthobunyavirus, which is the largest virus genus in the Family Peribunyaviridae and even Class Bunyaviricetes.
Han Gao   +8 more
doaj   +4 more sources

Phylogenetic Analysis of Lednice Orthobunyavirus [PDF]

open access: goldMicroorganisms, 2019
Lednice virus (LEDV) has been detected in Culex modestus mosquitoes in several European countries within the last six decades. In this study, phylogenetic analyses of the complete genome segments confirm that LEDV belongs to the Turlock orthobunyavirus ...
Rebeka Lucijana Berčič   +7 more
doaj   +6 more sources

Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models. [PDF]

open access: yesPLoS Neglected Tropical Diseases
Reassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen   +7 more
doaj   +3 more sources

Reverse Genetics System for Shuni Virus, an Emerging Orthobunyavirus with Zoonotic Potential [PDF]

open access: goldViruses, 2020
The genus Orthobunyavirus (family Peribunyaviridae, order Bunyavirales) comprises over 170 named mosquito- and midge-borne viruses, several of which cause severe disease in animals or humans. Their three-segmented genomes enable reassortment with related
Judith Oymans   +7 more
doaj   +2 more sources

Molecular identification and cross-species transmission effects analysis of a novel Orthobunyavirus isolated from Geese in China [PDF]

open access: yesPoultry Science
Orthobunyavirus is a class of RNA viruses that includes hundreds of viruses, many of which are important zoonotic pathogens causing clinical symptoms in livestock and humans.
Huiping Liang   +12 more
doaj   +2 more sources

Genomic characterization of arboviruses discovered between the 1950s and 1980s [PDF]

open access: yesJournal of Virology
Arthropod-borne viruses (arboviruses) pose a major threat to global public health, impacting both human and animal health. Genomic characterization is important for arboviruses because it allows for an understanding of their evolution and improves timely
Ingra M. Claro   +7 more
doaj   +2 more sources

The La Crosse virus Gc head domain is a major determinant of infection and pathogenesis [PDF]

open access: yesJournal of Virology
How orthobunyaviruses establish infections and disseminate to cause disease is not well understood. In a previous study using the in vivo evolution of La Crosse virus (LACV), we discovered a cluster of mutations localizing to the LACV Gc head domain ...
Ariana Dedvukaj   +6 more
doaj   +2 more sources

INVESTIGAÇÃO SOROLÓGICA PARA AS ARBOVIROSES EM ÁREAS DE EXPLORAÇÃO MINERAL NO ESTADO DO PARÁ

open access: yesBrazilian Journal of Infectious Diseases, 2023
Introdução: O estado do Pará vem sofrendo grandes transformações ambientais, dentre elas a exploração mineral e o desmatamento, o que aumenta o risco de infecção humana por arbovírus. Assim, objetiva-se demonstrar, através da presença de anticorpos IgM e
Letícia Françadas Mercês   +7 more
doaj   +1 more source

Mammals Preferred: Reassortment of Batai and Bunyamwera orthobunyavirus Occurs in Mammalian but Not Insect Cells

open access: yesViruses, 2021
Reassortment is a viral genome-segment recomposition known for many viruses, including the orthobunyaviruses. The co-infection of a host cell with two viruses of the same serogroup, such as the Bunyamwera orthobunyavirus and the Batai orthobunyavirus ...
Anna Heitmann   +9 more
doaj   +1 more source

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