The Role of Orthobunyavirus Glycoprotein Gc in the Viral Life Cycle: From Viral Entry to Egress [PDF]
Orthobunyavirus refers to the virus members within the Genus Orthobunyavirus, which is the largest virus genus in the Family Peribunyaviridae and even Class Bunyaviricetes.
Han Gao +8 more
doaj +4 more sources
Phylogenetic Analysis of Lednice Orthobunyavirus [PDF]
Lednice virus (LEDV) has been detected in Culex modestus mosquitoes in several European countries within the last six decades. In this study, phylogenetic analyses of the complete genome segments confirm that LEDV belongs to the Turlock orthobunyavirus ...
Rebeka Lucijana Berčič +7 more
doaj +6 more sources
Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models. [PDF]
Reassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen +7 more
doaj +3 more sources
Reverse Genetics System for Shuni Virus, an Emerging Orthobunyavirus with Zoonotic Potential [PDF]
The genus Orthobunyavirus (family Peribunyaviridae, order Bunyavirales) comprises over 170 named mosquito- and midge-borne viruses, several of which cause severe disease in animals or humans. Their three-segmented genomes enable reassortment with related
Judith Oymans +7 more
doaj +2 more sources
Molecular identification and cross-species transmission effects analysis of a novel Orthobunyavirus isolated from Geese in China [PDF]
Orthobunyavirus is a class of RNA viruses that includes hundreds of viruses, many of which are important zoonotic pathogens causing clinical symptoms in livestock and humans.
Huiping Liang +12 more
doaj +2 more sources
Genomic characterization of arboviruses discovered between the 1950s and 1980s [PDF]
Arthropod-borne viruses (arboviruses) pose a major threat to global public health, impacting both human and animal health. Genomic characterization is important for arboviruses because it allows for an understanding of their evolution and improves timely
Ingra M. Claro +7 more
doaj +2 more sources
The La Crosse virus Gc head domain is a major determinant of infection and pathogenesis [PDF]
How orthobunyaviruses establish infections and disseminate to cause disease is not well understood. In a previous study using the in vivo evolution of La Crosse virus (LACV), we discovered a cluster of mutations localizing to the LACV Gc head domain ...
Ariana Dedvukaj +6 more
doaj +2 more sources
A mix-and-match reverse genetics system for evaluating genetic determinants of orthobunyavirus neurological disease. [PDF]
Miettinen HM, Abbott MJ, Evans AB.
europepmc +3 more sources
INVESTIGAÇÃO SOROLÓGICA PARA AS ARBOVIROSES EM ÁREAS DE EXPLORAÇÃO MINERAL NO ESTADO DO PARÁ
Introdução: O estado do Pará vem sofrendo grandes transformações ambientais, dentre elas a exploração mineral e o desmatamento, o que aumenta o risco de infecção humana por arbovírus. Assim, objetiva-se demonstrar, através da presença de anticorpos IgM e
Letícia Françadas Mercês +7 more
doaj +1 more source
Reassortment is a viral genome-segment recomposition known for many viruses, including the orthobunyaviruses. The co-infection of a host cell with two viruses of the same serogroup, such as the Bunyamwera orthobunyavirus and the Batai orthobunyavirus ...
Anna Heitmann +9 more
doaj +1 more source

