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IN VITRO AND IN VIVO STUDIES OF RIBAVIRIN ACTION ON BRAZILIAN ORTHOBUNYAVIRUS
The American Journal of Tropical Medicine and Hygiene, 2006Oropouche, Caraparu, Guama, Guaroa, and Tacaiuma are viruses (genus Orthobunyavirus) that cause human febrile illnesses and encephalitis. The goal of this study was to evaluate the antiviral action of ribavirin on these orthobunyaviruses to achieve a therapeutical agent to treat the diseases caused by these viruses.
Luiz Tadeu Moraes Figueiredo+3 more
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Identification of a phylogenetically distinct orthobunyavirus from group C [PDF]
Apeu virus (APEUV) (family Bunyaviridae, genus Orthobunyavirus) was plaque purified and characterised by serological and molecular analysis. Neutralising assays confirmed cross-reactivity between purified APEUV clones and the Caraparu virus complex of group C orthobunyaviruses. Partial sequencing of the L, M and S segments of one APEUV clone (APEUV-CL5)
Marieta T.A. Assis+12 more
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Orthobunyavirus Family of Emerging Viruses
2020Yassine Kasmi, Moulay Mustapha Ennaji
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