Results 31 to 40 of about 9,735 (200)
Andrology, Volume 11, Issue 4, Page 756-769, May 2023., 2023 Abstract Background It has been estimated that microorganisms are involved in the pathogenesis of approximately 20% of all cancers. Testicular germ cell tumours (TGCTs) are the most common type of malignancy in young men and arise from the precursor cell, germ cell neoplasia in situ (GCNIS).
Nina Mørup +5 more
wiley +1 more source
Orthobunyavirus Ultrastructure and the Curious Tripodal Glycoprotein Spike [PDF]
PLoS Pathogens, 2013 The genus Orthobunyavirus within the family Bunyaviridae constitutes an expanding group of emerging viruses, which threaten human and animal health. Despite the medical importance, little is known about orthobunyavirus structure, a prerequisite for understanding virus assembly and entry.
Bowden, Thomas +6 more
openaire +7 more sources
EFSA Journal, Volume 21, Issue 3, March 2023., 2023 Abstract In the context of the initiative ‘CP‐g‐22‐04.01 Direct grants to Member States’ authorities', EFSA was requested to develop and conduct a prioritisation of zoonotic diseases, in collaboration with Member States, to identify priorities for the establishment of a coordinated surveillance system under the One Health approach.
European Food Safety Authority (EFSA) +7 more
wiley +1 more source
Orthobunyavirus spike architecture and recognition by neutralizing antibodies [PDF]
Nature Communications, 2019 AbstractOrthobunyaviruses (OBVs) form a distinct genus of arthropod-borne bunyaviruses that can cause severe disease upon zoonotic transmission to humans. Antigenic drift or genome segment re-assortment have in the past resulted in new pathogenic OBVs, making them potential candidates for causing emerging zoonoses in the future. Low-resolution electron
Jan Hellert +8 more
openaire +4 more sources
Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice [PDF]
, 2016 Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain of Schmallenberg virus (SBV) serially passaged in tissue culture ...
Aislynn Taggart +13 more
core +1 more source
Culex tarsalis is a competent vector species for Cache Valley virus [PDF]
, 2018 Background: Cache Valley virus (CVV) is a mosquito-borne orthobunyavirus endemic in North America. The virus is an important agricultural pathogen leading to abortion and embryonic lethality in ruminant species, especially sheep.
Alto, Barry W. +10 more
core +1 more source
Molecular characterization of Umbre virus (Bunyaviridae)
Virology Journal, 2008 Umbre (UMB) virus was first isolated from India in 1955 and classified as Orthobunyavirus (Turlock serogroup). Eight isolates of this virus, isolated from Culex mosquitoes were characterized on the basis of partial glycoprotein (G2) gene.
Mourya Devendra T +2 more
doaj +1 more source
Epidemiology of Shuni Virus in Horses in South Africa
Viruses, 2021 The Orthobunyavirus genus, family Peribunyaviridae, contains several important emerging and re-emerging arboviruses of veterinary and medical importance.
Thopisang P. Motlou +2 more
doaj +1 more source
Second Human Case of Cache Valley Virus Disease
Emerging Infectious Diseases, 2006 We document the second known case of Cache Valley virus disease in a human. Cache Valley virus disease is rarely diagnosed in North America, in part because laboratories rarely test for it.
Grant L. Campbell +8 more
doaj +1 more source
Reverse Genetics System for Shuni Virus, an Emerging Orthobunyavirus with Zoonotic Potential
Viruses, 2020 The genus Orthobunyavirus (family Peribunyaviridae, order Bunyavirales) comprises over 170 named mosquito- and midge-borne viruses, several of which cause severe disease in animals or humans. Their three-segmented genomes enable reassortment with related
Judith Oymans +7 more
doaj +1 more source