The Role of Temperature in Transmission of Zoonotic Arboviruses
Viruses, 2019 We reviewed the literature on the role of temperature in transmission of zoonotic arboviruses. Vector competence is affected by both direct and indirect effects of temperature, and generally increases with increasing temperature, but results may vary by ...
Alexander T. Ciota, Alexander C. Keyel
doaj +1 more source
Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]
, 2018 Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D. +15 more
core +1 more source
‘Schmallenberg virus’ – a novel orthobunyavirus emerging in Europe
Epidemiology and Infection, 2012 SUMMARYIn 2011, a novel orthobunyavirus of the Simbu serogroup, the Schmallenberg virus (SBV), was discovered using a metagenomic approach. SBV caused a large epidemic in Europe in ruminants. As with related viruses such as Akabane virus, it appears to be transmitted by biting midges.
Beer, M. +2 more
openaire +3 more sources
Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda. [PDF]
, 2019 Febrile illness is a major burden in African children, and non-malarial causes of fever are uncertain. In this retrospective exploratory study, we used metagenomic next-generation sequencing (mNGS) to evaluate serum, nasopharyngeal, and stool specimens ...
Byaruhanga, Oswald +17 more
core +3 more sources
The antiviral RNAi response in vector and non-vector cells against orthobunya viruses [PDF]
, 2017 Background: Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and
Bausch, DG +9 more
core +5 more sources
Shuni Virus in Wildlife and Nonequine Domestic Animals, South Africa
Emerging Infectious Diseases, 2020 We screened nonequine animals with unexplained neurologic signs or death in South Africa during 2010–2018 for Shuni virus (SHUV). SHUV was detected in 3.3% of wildlife, 1.1% of domestic, and 2.0% of avian species.
Jumari Steyn +13 more
doaj +1 more source
NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery [PDF]
, 2014 Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and ...
Barry, Gerald +10 more
core +3 more sources
Homology modeling and molecular dynamics provide structural insights into tospovirus nucleoprotein [PDF]
, 2016 Background: Tospovirus is a plant-infecting genus within the family Bunyaviridae, which also includes four animalinfecting genera: Hantavirus, Nairovirus, Phlebovirus and Orthobunyavirus.
Barbosa, João Alexandre Ribeiro Gonçalves +6 more
core +1 more source
Molecular epidemiology of Akabane virus in Taiwan
Veterinary Medicine and Science, 2022 Background Akabane virus (AKAV) is a teratogenic and neuropathogenic arbovirus that infects livestock and wild animals. AKAVs are endemic arboviruses from dairy farms in Taiwan in 1989, and the first sequence was detected in cattle with nonsuppurative ...
Hau‐You Tzeng +4 more
doaj +1 more source
Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]
, 2013 The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L. +8 more
core +3 more sources