Shuni Virus in Wildlife and Nonequine Domestic Animals, South Africa
We screened nonequine animals with unexplained neurologic signs or death in South Africa during 2010–2018 for Shuni virus (SHUV). SHUV was detected in 3.3% of wildlife, 1.1% of domestic, and 2.0% of avian species.
Jumari Steyn +13 more
doaj +1 more source
A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus
Since the intricate and complex steps in pathogenesis and host-viral interactions of arthropod-borne viruses or arboviruses are not completely understood, the multi-omics approaches, which encompass proteomics, transcriptomics, genomics and metabolomics network analysis, are of great importance.
Rafaela dos S. Peinado +3 more
openaire +4 more sources
NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery [PDF]
Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and ...
Barry, Gerald +10 more
core +3 more sources
The antiviral RNAi response in vector and non-vector cells against orthobunya viruses [PDF]
Background: Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and
Bausch, DG +9 more
core +5 more sources
Homology modeling and molecular dynamics provide structural insights into tospovirus nucleoprotein [PDF]
Background: Tospovirus is a plant-infecting genus within the family Bunyaviridae, which also includes four animalinfecting genera: Hantavirus, Nairovirus, Phlebovirus and Orthobunyavirus.
Barbosa, João Alexandre Ribeiro Gonçalves +6 more
core +1 more source
Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L. +8 more
core +3 more sources
Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France
We report the discovery of a new orthobunyavirus, Cristoli virus, by means of shotgun metagenomics. The virus was identified in an immunodepressed patient with fatal encephalitis.
Christophe Rodriguez +10 more
doaj +1 more source
Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin +2 more
core +1 more source
Arboviral diseases spread by Culicoides biting midges have been introduced into Europe by unknown means. A possible route is the carriage of midges with cut flowers shipped to flower markets. We sampled Culicoides in and around a cut flower farm in Kenya; midges were caught in the vicinity and a greenhouse, but not where flowers are processed.
Jessica Eleanor Stokes +3 more
wiley +1 more source
The family Bunyaviridae has more than 530 members that are distributed among five genera or remain to be classified. The genus Orthobunyavirus is the most diverse bunyaviral genus with more than 220 viruses that have been assigned to more than 18 ...
Alexey M. Shchetinin +6 more
doaj +1 more source

