Results 101 to 110 of about 49,228 (265)

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Shaping Future Children, Sex Selection, and “Normal” Human Capacities

Bioethics, EarlyView.
ABSTRACT If we think that parents have an obligation to have a healthy child then we need to know what counts as healthy, when male and female children are born with very different capacities. If we give up on the idea that our obligations to use technologies of genetic selection are discharged once we try to secure the birth of a healthy child, as ...
Robert Sparrow
wiley   +1 more source

Behaviour Support in Dentistry Core Outcomes (BeSiDe‐CO): A Core Outcome Set Development Study

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To develop a Core Outcome Set suitable for adults and children for use in studies of Dental Behaviour Support (DBS) techniques, including non‐pharmacological DBS, sedation and General Anaesthesia research. Methods Two systematic reviews generated a preliminary list of candidate outcomes that were shared with Key Stakeholders (KSG ...
Caoimhin Mac Giolla Phadraig, Isabel C. Olegário, Shaelynn Hsu, Maryam Al Zayer, Aisyah Binti Ahmad Fisal, Alison Dougall, Gareth B. Kitchen, Henry F. Duncan, Sarah Baker, Sharat Pani, Sreekanth Kumar Mallineni, Mandy Daly, The BeSiDe COS Collaboration, Tracey Scott, Carolyn Akintola, Éilish Burke, Steve Moore, Barbara Vallo, Jacobo Posse Limerese, Karin Alexandra Van Nes, Maiken Bagger, Olive Healy, Andrew Geddis‐Regan   +22 more
wiley   +1 more source

A Randomised Controlled Trial Comparing a One‐Piece Zirconia Tissue‐Level Implant and Two‐Piece Titanium Bone‐Level Implant for Maxillary Single Tooth Replacement—3 year Results

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This RCT evaluated and compared the clinical performance of zirconia and titanium dental implants placed in the maxillary premolar region. Outcomes were assessed 3 years after prosthetic loading and included marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs ...
J. H. W. de Beus, M. S. Cune, L. Muijselaar, J. W. A. Slot, C. Jensen‐Louwerse, S. la Bastide‐van Gemert, H. J. A. Meijer, G. M. Raghoebar, U. Schepke   +8 more
wiley   +1 more source

Patch Test Reactions to Dental Materials: A Retrospective Single‐Centre Study

Contact Dermatitis, EarlyView.
In this retrospective single‐centre study of 439 adults referred for suspected delayed‐type hypersensitivity to dental materials, 50.1% had at least one positive patch test reaction, most often to metals. Nickel (23.0%) and palladium (16.6%) pre‐dominated, whilst methacrylate positivity was uncommon (6.2%) and not fully captured by HEMA alone.
Mojca Bizjak‐Suran, Manca Marčun, Mitja Košnik, Dejan Dinevski   +3 more
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

Clinical Efficacy of CBCT and 3D‐Printed Replicas in Molar Autotransplantation: A Controlled Clinical Trial

Dental Traumatology, Volume 41, Issue 2, Page 161-170, April 2025.
ABSTRACT Background/Aim To evaluate the efficacy of the combined cone‐beam (CBCT)/3D‐replicas protocol on the clinical and radiographic outcomes of autotransplanted molars. Material and Methods Controlled clinical trial registered ISRCTN13563091 from August 2019 to September 2022.
Miks Lejnieks, Ilze Akota, Gundega Jākobsone, Laura Neimane, Sergio E. Uribe   +4 more
wiley   +1 more source

Orthodontic Treatment [PDF]

, 2020
LEONHARDT HOWARD J, MARCHETTO JOHN JOSEPH, GENOVESE JORGE, RICHARDSON ALEX   +3 more
openaire   +3 more sources

Dental Splints in Dentoalveolar Trauma: An Overview of Public Healthcare Services in Brazil

Dental Traumatology, EarlyView.
ABSTRACT Background/Aim The prognosis of traumatized teeth might be influenced by the type and quality of the dental splint. This prospective observational study was aimed to evaluate the indications and quality of dental splints performed in a comprehensive public oral health service in the city of Uberlândia, Brazil.
Caroline Garcia Orsi, Roberta Alves de Oliveira, Carlos Daniel Sturaro Junqueira, André Luis Faria‐e‐Silva, Liran Levin, Carlos José Soares, Priscilla Barbosa Ferreira Soares   +6 more
wiley   +1 more source

Knowledge, Attitudes, and Practices Toward Clinical Photography for Pediatric Dental Trauma Documentation: A Multinational Mixed‐Methods Cross‐Sectional Study

Dental Traumatology, EarlyView.
ABSTRACT Background/Aim Traumatic dental injuries (TDIs) require accurate documentation for diagnosis, treatment planning, and medico‐legal purposes. International guidelines strongly recommend the use of clinical photography, yet its use among pediatric dentists has not been consistently evaluated across countries. This study aimed to assess pediatric
Narmin Helal, Nitesh Tewari, Reem Wahby, Ahmed Fawzy   +3 more
wiley   +1 more source