Results 111 to 120 of about 48,778 (265)

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

open access: yesCell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu   +12 more
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

open access: yesCell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen   +10 more
wiley   +1 more source

Clinical Efficacy of CBCT and 3D‐Printed Replicas in Molar Autotransplantation: A Controlled Clinical Trial

open access: yesDental Traumatology, Volume 41, Issue 2, Page 161-170, April 2025.
ABSTRACT Background/Aim To evaluate the efficacy of the combined cone‐beam (CBCT)/3D‐replicas protocol on the clinical and radiographic outcomes of autotransplanted molars. Material and Methods Controlled clinical trial registered ISRCTN13563091 from August 2019 to September 2022.
Miks Lejnieks   +4 more
wiley   +1 more source

Prevalence of Post‐Operative Complications in Autotransplanted Teeth: A Long‐Term Retrospective Cohort

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background/Aims To evaluate the prevalence and timing of post‐operative complications following tooth autotransplantation, identify factors associated with earlier diagnosis, and report long‐term survival and success rates. Materials and Methods A single‐centre retrospective cohort study was conducted at a Czech university dental clinic (2003 ...
Juraj Marton   +5 more
wiley   +1 more source

SOS Dental Trauma—An Artificial Intelligence Chatbot via WhatsApp for Guiding Patients After Dental Trauma

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background Traumatic dental injuries (TDIs) are highly prevalent worldwide and require immediate and appropriate management to ensure favorable outcomes. The aim of the study was to develop and validate SOS Dental Trauma, an interactive artificial intelligence‐based chatbot integrated with WhatsApp.
Luana Beatriz das Portas Luiz   +9 more
wiley   +1 more source

Dental Splints in Dentoalveolar Trauma: An Overview of Public Healthcare Services in Brazil

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background/Aim The prognosis of traumatized teeth might be influenced by the type and quality of the dental splint. This prospective observational study was aimed to evaluate the indications and quality of dental splints performed in a comprehensive public oral health service in the city of Uberlândia, Brazil.
Caroline Garcia Orsi   +6 more
wiley   +1 more source

Knowledge, Attitudes, and Practices Toward Clinical Photography for Pediatric Dental Trauma Documentation: A Multinational Mixed‐Methods Cross‐Sectional Study

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background/Aim Traumatic dental injuries (TDIs) require accurate documentation for diagnosis, treatment planning, and medico‐legal purposes. International guidelines strongly recommend the use of clinical photography, yet its use among pediatric dentists has not been consistently evaluated across countries. This study aimed to assess pediatric
Narmin Helal   +3 more
wiley   +1 more source

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