Results 31 to 40 of about 21,315 (262)

On incomplete orthogonal arrays

Journal of Combinatorial Theory, Series A, 1985
\textit{E. T. Parker} [Proc. Am. Math. Soc. 13, 219-221 (1962; Zbl 0105.015)] remarked that if an incomplete orthogonal array with parameters (1,r,s,k,2) exists then \(s\geq (r-1)k\). As the author shows, this result is easily extended to incomplete orthogonal arrays (1,r,s,k,t) for which \(s\geq (r-t+1)k\). \textit{K. A. Bush} [Ann. Math.
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Applications of Taguchi Methods in Prestressed Concrete Structures [PDF]

预应力技术
Prestressed concrete (PSC) structures are fundamental to bridges, buildings, and other critical infrastructure, requiring design approaches that balance mechanical performance, durability, and cost throughout the service life. Because PSC systems involve
Jose Antonio Lozano-Galant, Carlos Gisbert, Ye Xia, Fidel Lozano-Galant, Alejandro Mungaray   +4 more
doaj   +1 more source

Constructions of augmented orthogonal arrays [PDF]

Journal of Combinatorial Designs, 2018
AbstractAugmented orthogonal arrays (AOAs) were introduced by Stinson, who showed the equivalence between ideal ramp schemes and AOAs (Discrete Math. 341 (2018), 299–307). In this paper, we show that there is an AOAif and only if there is an OAwhich can be partitioned intosubarrays, each being an OA, and that there is a linear AOAif and only if there ...
Xin Wang, Lijun Ji, Yun Li, Miao Liang
openaire   +3 more sources

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

Orthogonal Genetic Algorithm for Planar Thinned Array Designs

International Journal of Antennas and Propagation, 2012
An orthogonal genetic algorithm (OGA) is applied to optimize the planar thinned array with a minimum peak sidelobe level. The method is a genetic algorithm based on orthogonal design.
Li Zhang, Yong-Chang Jiao, Bo Chen, Hong Li   +3 more
doaj   +1 more source

Rafting of Ni‐Based Superalloys Under Multiaxial Load as Understood by Phase‐Field Simulations and Critical Experiments

Advanced Engineering Materials, EarlyView.
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan, David Bürger, Gunther Eggeler, Oleg Shchyglo, Ingo Steinbach, Muhammad Adil Ali   +5 more
wiley   +1 more source

Feasibility of Orthogonal Taguchi Arrays for Determining Parameter Trends in MDT

Current Directions in Biomedical Engineering
Huge parameter studies are usually conducted to optimize and characterize systems for steering magnetic nanoparticles in magnetic drug targeting (MDT). Thus, many simulations or measurements are needed to determine the system which is time-consuming and ...
Thalmayer Angelika S., Xiao Keyu, Fischer Georg, Lübke Maximilian   +3 more
doaj   +1 more source

Multimodal Data‐Driven Microstructure Characterization

Advanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang, Santiago Benito, Özge Özgün, Sebastian Weber, Markus Stricker   +4 more
wiley   +1 more source