Spatially Encoded Protocell Network for Non‐Cascaded Parallel Biocomputation
Advanced Science, EarlyView.A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Shuqi Wu, Liangfei Tian
wiley +1 more source
CryoTriplane: triplane-based neural radiance field representation for high-resolution cryo-EM 3D homogeneous reconstruction. [PDF]
BioinformaticsCheng Y, He B, Zeng Q, Zhang F, Han R.
europepmc +1 more source
Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
Advanced Science, EarlyView.By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
Symmetry‐Imposed Selection Rules for Excitations of Nontrivial Plasmonic Topologies
Advanced Science, EarlyView.A unified group‐theory selection rule governs the excitation of vectorial nearfield topologies across three plasmonic spin states. Derived from first principles, it predicts spin–orbit vortex splitting and multidimensional nested vortices, confirmed by phase‐resolved in situ measurements.
Jie Yang +14 more
wiley +1 more source
S2V-DREME: a time-resolved slice-to-volume MR image reconstruction framework with dynamic reconstruction and motion estimation. [PDF]
Phys Med BiolQian X, Shao HC, Deng J, Dai Y, Zhang Y.
europepmc +1 more source
Advanced Science, EarlyView.ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao +6 more
wiley +1 more source
Identification of Black Bean Geographical Origins Using Portable NIR Spectroscopy Combined with Fuzzy Orthogonal Linear Discriminant Analysis and Its Kernel Extension. [PDF]
FoodsDong J, Wu X, Xie C, Zhou J, Wu B.
europepmc +1 more source
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Alkali-Fused Coal Gasification Fine Slag for Simulated Phenolic Wastewater Treatment: Adsorption-Oxidation Performance and Mechanistic Investigation. [PDF]
ACS OmegaHu W +6 more
europepmc +1 more source
Advanced Science, EarlyView.A metasurface‐enabled helical wavefront fingerprint (MHWF) paradigm is proposed for quantitative and specific retrieval of a liquid medium's refractive index and extinction coefficient. The liquid's complex dielectric response governs the wavefront evolution of the metasurface‐generated focused vortex beam, forming a distinctive three‐dimensional ...
Yuting Zhou +10 more
wiley +1 more source