Results 31 to 40 of about 136,791 (265)

Generation of arbitrary cylindrical vector vortex beams with cross-polarized modulation

open access: yesResults in Physics, 2020
Cylindrical vector vortex beams (CVVBs), possessing both spatially nonuniform phase and polarization distribution, have attracted research interests in many applications due to their unique optical properties.
Junmin Liu   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Multiband Circular Polarizer Based on Fission Transmission of Linearly Polarized Wave for X-Band Applications

open access: yesJournal of Electrical and Computer Engineering, 2016
A multiband circular polarizer based on fission transmission of linearly polarized wave for x-band application is proposed, which is constructed of 2 × 2 metallic strips array. The linear-to-circular polarization conversion is obtained by decomposing the
Farman Ali Mangi   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Cell Engineering and Cultivation of Chinese Hamster Ovary Cells for the Development of Orthogonal Eukaryotic Cell-free Translation Systems

open access: yesFrontiers in Molecular Biosciences, 2022
The investigation of protein structures, functions and interactions often requires modifications to adapt protein properties to the specific application.
Jeffrey L. Schloßhauer   +7 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Capacity of a class of symmetric relay networks with orthogonal components

open access: yesIET Communications, 2010
In this study, the authors extend the concept of relay channel with orthogonal components to define a class of symmetric relay networks with orthogonal components named symmetric orthogonal relay network. In the defined network, the channels diverge from each node sender use different frequency bands whereas the channels converge to each node receiver ...
Leila Ghabeli, Mohammad Reza Aref
openaire   +1 more source

IMPROVEMENT OF ALGORITHM FOR FORMATION OF ORTHOGONAL COMPONENTS OF INPUT VALUES IN MICROPROCESSOR RELAY PROTECTION OF POWER LINES IN DISTRIBUTION NETWORKS

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014
The paper considers a new algorithm for formation of orthogonal components of input values in microprocessor relay protection of power lines in distribution networks.
F. A. Romaniuk, M. A. Shevaldin
doaj  

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