Results 31 to 40 of about 26,581 (261)
Orthogonal Designs and a Cubic Binary Function [PDF]
IEEE Transactions on Information Theory, 2013 Orthogonal designs are fundamental mathematical notions used in the construction of space time block codes for wireless transmissions. Designs have two important parameters, the rate and the decoding delay; the main problem of the theory is to construct designs maximizing the rate and minimizing the decoding delay.
Morier-Genoud, Sophie +1 more
openaire +4 more sources
Statistical Theory and Related FieldsSpace-filling designs with superior low-dimensional properties are highly required in computer experiments. Strong orthogonal arrays (SOAs) represent a class of such designs that outperform ordinary orthogonal arrays in their stratification properties ...
Qiang Gao +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Redesigning metabolism based on orthogonality principles
Nature Communications, 2017 Growth-coupled designs for chemical production are limited by native metabolic networks’ optimality for growth. Here, the authors introduce pathway orthogonality as a measure of the independence of biomass and chemical production pathways, identify ...
Aditya Vikram Pandit +2 more
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Study of Behaviours via Visitable Paths [PDF]
Logical Methods in Computer Science, 2018 Around 2000, J.-Y. Girard developed a logical theory, called Ludics. This theory was a step in his program of Geometry of Interaction, the aim of which being to account for the dynamics of logical proofs.
Christophe Fouqueré, Myriam Quatrini
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Linear and Decoupled Decoders for Dual-Polarized Antenna-Based MIMO Systems
Sensors, 2020 Quaternion orthogonal designs (QODs) have been used to design STBCs that provide improved performance in terms of various design parameters. In this paper, we show that all QODs obtained from generic iterative construction techniques based on the Adams ...
Sara Shakil Qureshi +2 more
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Spreading Sequence Design and Theoretical Limits for Quasisynchronous CDMA Systems
EURASIP Journal on Wireless Communications and Networking, 2004 For various quasisynchronous (QS) CDMA systems such as LAS-CDMA system which emerged recently, in order to reduce or eliminate the multiple access interference and multipath interference, it is required to design a set of spreading sequences which are ...
Fan Pingzhi
doaj +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source