Results 61 to 70 of about 49,792 (241)

Profiling of Integrin Isoforms on Lung‐Tropic Exosomes by Spectrally and Kinetically Multiplexed Single‐Molecule Imaging

open access: yesAdvanced Science, EarlyView.
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu   +10 more
wiley   +1 more source

Alamouti OFDM/OQAM systems with time reversal technique [PDF]

open access: yes, 2015
Orthogonal Frequency Division Multiplexing with Offset Quadrature Amplitude Modulation (OFDM/OQAM) is a multicarrier modulation scheme that can be considered as an alternative to the conventional Orthogonal Frequency Division Multiplexing (OFDM) with ...
Blel, Ilhem, Bouallegue, Ridha
core  

Real‐Time Visualization of Isoform‐Specific RAF‐KRAS Interactions in Living Cells Using FRET‐BRET Hybrid Biosensors

open access: yesAdvanced Science, EarlyView.
Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go   +12 more
wiley   +1 more source

Orthogonal Chirp Division Multiplexing for Underwater Acoustic Communication

open access: yesSensors, 2018
The objective of this study is to investigate a novel Underwater Acoustic Communication (UWAC) system based on a modulated chirp signal termed as Orthogonal Chirp Division Multiplexing (OCDM).
Yiqi Bai, Pierre-Jean Bouvet
doaj   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

Modelling the satellite communication links with orthogonal frequency-division multiplexing

open access: yesTransport, 2016
Global technologies of data transmission in real time are developing constantly. Therefore, modelling of messages transmission through satellite constellations is an actual problem.
Volodymir Kharchenko   +3 more
doaj   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

open access: yesAdvanced Science, EarlyView.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu   +8 more
wiley   +1 more source

Adaptive-Modulation-Enabled WDM Impairment Reduction in Multichannel Optical OFDM Transmission Systems for Next-Generation PONs

open access: yesIEEE Photonics Journal, 2010
The transmission performance of multichannel adaptively modulated optical orthogonal frequency-division multiplexing (AMOOFDM) signals is investigated numerically, for the first time, in optical-amplification-free and chromatic-dispersion-compensation ...
E. Giacoumidis   +4 more
doaj   +1 more source

Group-indexed orthogonal frequency division multiplexing index modulation aided performance trade off

open access: yesETRI Journal, 2022
In this study, a novel group-indexed orthogonal frequency division multiplexing index modulation (OFDM-IM) scheme is proposed to achieve a tradeoff between spectral efficiency (SE) and bit-error-rate (BER) performance.
Thomas Wilfred Edison Athisaya Anushya   +2 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

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