Results 51 to 60 of about 981,446 (269)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Orthogonal Matching Pursuit: A Brownian Motion Analysis [PDF]
IEEE Transactions on Signal Processing, 2012 A well-known analysis of Tropp and Gilbert shows that orthogonal matching pursuit (OMP) can recover a k-sparse n-dimensional real vector from 4 k log(n) noise-free linear measurements obtained through a random Gaussian measurement matrix with a probability that approaches one as n approaches infinity. This work strengthens this result by showing that a
Alyson K. Fletcher, Sundeep Rangan
openaire +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
IET Networks, 2019 This study proposes a construction method of deterministic measurement matrix based on a correlation criterion. On this basis, the authors investigated the massive multiple‐input and multiple‐output (MIMO) channel estimation algorithm using the ...
Ruijin Ma, Huisheng Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
On the difference between orthogonal matching pursuit and orthogonal least squares
, 2007 — Greedy algorithms are often used to solve underdetermined inverse problems when the solution is constrained to be sparse, i.e. the solution is only expected to have a relatively small number of non-zero elements.
Blumensath, T. +3 more
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Fast Non-Negative Orthogonal Matching Pursuit [PDF]
IEEE Signal Processing Letters, 2015 One of the important classes of sparse signals is the non-negative signals. Many algorithms have already been proposed to recover such non-negative representations, where greedy and convex relaxed algorithms are among the most popular methods. The greedy techniques have been modified to incorporate the non-negativity of the representations.
Yaghoobi, Mehrdad +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
A Reducing Iteration Orthogonal Matching Pursuit Algorithm for Compressive Sensing
Tsinghua Science and Technology, 2016 In recent years, Compressed Sensing (CS) has been a hot research topic. It has a wide range of applications, such as image processing and speech signal processing owing to its characteristic of removing redundant information by reducing the sampling rate.
Rui Wang +3 more
doaj +1 more source