Results 211 to 220 of about 1,069,691 (320)

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Chemical Doping Engineering of Polarization and Topological Textures in van der Waals Ferroelectric CuInP2S6

open access: yesAdvanced Science, EarlyView.
Our work reports that Li⁺ doping in CuInP2S₆ induces coexistence of high‐ and low‐polarization states, which fosters a rich spectrum of topological polar textures, such as bubbles and labyrinth domains. An unconventional flexoelectric effect is also discovered, where strain gradients can mechanically manipulate these polarization states and their ...
Lei Gao   +12 more
wiley   +1 more source

Membrane Perturbations and Assay Interferences by Ivermectin Explain Its In Vitro SARS-CoV-2 Antiviral Activities and Lack of Translatability. [PDF]

open access: yesJ Med Chem
Eastman RT   +8 more
europepmc   +1 more source

Broadband Achromatic Programmable Electromagnetic Camouflage via Fluidic‐Accessible Metasurface

open access: yesAdvanced Science, EarlyView.
A fluidic access metasurface enables dynamic, broadband electromagnetic illusions. By physically reconstructing conductive patterns with liquid metal, the metasurface achieves real‐time, pixel‐level control over phase dispersion. This allows for the programmable generation of arbitrary strong scattering point arrays, effectively deceiving high ...
Shipeng Liu   +14 more
wiley   +1 more source

Internal Phase Separation in Synthetic DNA Condensates. [PDF]

open access: yesAdv Sci (Weinh)
Tanase DA   +5 more
europepmc   +1 more source

Halogen‐Bond Coupled Halogenated‐π‐Conjugation Enables Giant Birefringence in Hydrogen‐Bonded Organic Frameworks

open access: yesAdvanced Science, EarlyView.
The perfect crystal packing achieved via the halogen‐bond (XB) coupled halogenated‐π‐conjugation strategy effectively induces an ultrahigh birefringence (Δn = 0.97), which exhibits promising potential in polarization control and phase modulation.
Miao‐Bin Xu   +6 more
wiley   +1 more source

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