Results 41 to 50 of about 178,760 (268)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Process parameter optimization and thermal shock resistance performance analysis of Al2O3-SiC coating

open access: yesJournal of Aeronautical Materials
To study the effect of spraying process parameters on the performance of Al2O3-SiC coatings,orthogonal tests are carried out to optimize the spraying process parameters,and the relationship between “spraying process- structure- bonding strength and ...
YUAN Xujiong   +7 more
doaj   +1 more source

Performance Analysis and Adjustment of Thermocompressor in Exhaust and Waste Heat Utilization System of 330 MW Air Cooling Unit

open access: yesZhongguo dianli, 2020
This paper introduces the configuration of the three-stage cascade exhaust and waste heat utilization system of the direct air cooling unit. In particular, the component structure and working principle of its most critical equipment, i.e., the ...
Zhikun HUANG   +5 more
doaj   +1 more source

A Rapid Method for the Determination of SBS Content Based on the Principle of Orthogonal Testing

open access: yesApplied Sciences, 2021
The performance of Styrene-butadiene-styrene (SBS) modified asphalt is closely related to the content of SBS modifier. In the production process of modified asphalt, a certain amount of additive such as sulfur and rubber oil may be added to reduce the ...
Gang Xu   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Design and Flow Characteristics of a Gravity-Driven Flow Control Valve

open access: yesMachines
Ultra-high-temperature and pressure downhole environments pose challenges for conventional electronic instruments to adapt to high-temperature formations, thereby restricting the application of downhole electronic tool technology in deep and ultra-deep ...
Qing Wang   +11 more
doaj   +1 more source

Study on performances and influence factors of mud foam

open access: yes矿业科学学报, 2019
Spontaneous combustion of coal is a serious threat to the safety production process of coal mine,the traditional technology of coal spontaneous combustion control such as grouting in not good.Mud foam is a new type of fire-fighting material,and the ...
Zhu Hongqing   +5 more
doaj   +1 more source

Applicable Conditions of Room-and-Pillar Mining Goaf Treatment Methods under a Traffic Load

open access: yesApplied Sciences, 2023
The disturbance depth of traffic load has a direct impact on the stability of a room-and-pillar mining goaf. To quantitatively calculate the relationship between the traffic load disturbance depth and influencing factors, 49 groups of horizontal ...
Fajin Zu   +4 more
doaj   +1 more source

An orthogonal test of the L -functions Ratios conjecture [PDF]

open access: yesProceedings of the London Mathematical Society, 2009
We test the predictions of the L-functions Ratios Conjecture for the family of cuspidal newforms of weight k and level N, with either k fixed and N --> oo through the primes or N=1 and k --> oo. We study the main and lower order terms in the 1-level density. We provide evidence for the Ratios Conjecture by computing and confirming its predictions
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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