Results 51 to 60 of about 189,105 (268)

Orthogonal Reference Surrogate Fuels for Operability Testing

Energies, 2020
The approval and evaluation process for sustainable aviation fuels (SAF) via ASTM D4054 is both cost- and volume-intensive, namely due to engine operability testing under severe conditions. Engine operability tests of combustor under figures of merit (FOM) limit phenomena are the fuel effects on lean blowout, high-altitude relight, and cold-start ...
Zhibin Yang, Robert Stachler, Joshua S. Heyne   +2 more
openaire   +3 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

MECHANICAL RESEARCH AND OPTIMIZATION OF BANANA STALK FIBER EXTRACTION [PDF]

Engenharia Agrícola
Banana stalk production for fiber is an important crop activity in southern China. The fiber extraction technology used has a great impact on the effectiveness and quality of the fiber from banana stalks.
Li Yue, Gao Yang, Huang Chun, Wei Shiquan, Li Yuan, Liang Dong   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Transmission Efficiency Test and Analysis of High-precision RV Reducer

Jixie chuandong, 2019
Based on the working principle of RV reducer， the combined， modular transmission efficiency test platform and its measurement and control system and software system that can meet the installation requirements of RV reducer with different specifications ...
Tong Guan, Honghai Xu, Xiongwei Xie, Linghui Wei   +3 more
doaj  

Multi-objective optimization of laser cladding parameters for 42CrMo surface based on GA-BP and NSGA-II algorithms

Hanjie xuebao
In order to solve the defects such as pits and microcracks on the surface of 42CrMo bearings, the repair process parameters matched by the high-strength steel of the main bearing were obtained.
Shun JIANG, Haiming ZHAO, Xianqiong ZHAO, Dongsheng LI, Lunlei YANG   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Testing hypotheses via orthogonalization

Classical hypothesis testing frameworks break down in contemporary settings in which null hypotheses are increasingly abstract, the same data are used to both generate and test hypotheses, and minimal assumptions about the underlying data are made. In this work, we propose a new framework for conducting valid hypothesis tests in broad contexts.
Dharamshi, Ameer, Zou, Runjia, Witten, Daniela   +2 more
openaire   +2 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source