Results 51 to 60 of about 14,369 (195)

A Novel Iminosugar UV-12 with Activity against the Diverse Viruses Influenza and Dengue (Novel Iminosugar Antiviral for Influenza and Dengue)

open access: yesViruses, 2015
Iminosugars are capable of targeting the life cycles of multiple viruses by blocking host endoplasmic reticulum α-glucosidase enzymes that are required for competent replication of a variety of enveloped, glycosylated viruses.
Kelly L. Warfield   +10 more
doaj   +1 more source

Virome of Rhipicephalus ticks by metagenomic analysis in Guangdong, southern China

open access: yesFrontiers in Microbiology, 2022
Tick-borne viruses (TBVs) have increasingly caused a global public health concern. This study collected Rhipicephalus ticks in Guangdong, southern China to identify RNA viruses.
Luanying Guo   +13 more
doaj   +1 more source

Virome Analysis Reveals Diverse and Divergent RNA Viruses in Wild Insect Pollinators in Beijing, China

open access: yesViruses, 2022
Insect pollinators provide major pollination services for wild plants and crops. Honeybee viruses can cause serious damage to honeybee colonies. However, viruses of other wild pollinating insects have yet to be fully explored.
Nannan Li   +3 more
doaj   +1 more source

Influenza pathogenesis: mechanisms of modulation by agent proteins

open access: yesЖурнал инфектологии, 2015
Modern concepts of the influence of the proteins from viruses-etiological agents of flu – Influenzavirus A, B and C (Orthomyxoviridae) – on the development of different elements of the main disease pathogenesis are analyzed in the review.
M. Yu. Shchelkanov   +7 more
doaj   +1 more source

Detection of a Reassortant Swine‐ and Human‐Origin H3N2 Influenza A Virus in Farmed Mink in British Columbia, Canada

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Introduction In December 2021, influenza A viruses (IAV) were detected in a population of farmed mink in British Columbia, Canada. Circulation of IAVs in farmed mink populations has raised public health concerns due to similarities between mustelid and human respiratory physiology, potentially facilitating spillover of zoonotic influenzas from
Kevin S. Kuchinski   +7 more
wiley   +1 more source

Tick-borne viruses and their diseases

open access: yesIatreia, 2018
Tick-borne viruses (TBVs) belong to the Flaviviridae, Bunyaviridae, Reoviridae, Asfarviridae and Orthomyxoviridae families and cause different diseases in humans and animals.
Molina Hoyos, Katterine   +3 more
doaj   +1 more source

Meta-transcriptomics for the diversity of tick-borne virus in Nujiang, Yunnan Province

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Ticks, an arthropod known for transmitting various pathogens such as viruses, bacteria, and fungi, pose a perpetual public health concern. A total of 2,570 ticks collected from Nujiang Prefecture in Yunnan Province between 2017 and 2022 were included in ...
Juan Wang   +12 more
doaj   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

open access: yesMedicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi   +9 more
wiley   +1 more source

Activation and inhibition of sirtuins: From bench to bedside

open access: yesMedicinal Research Reviews, Volume 45, Issue 2, Page 484-560, March 2025.
Abstract The sirtuin family comprises seven NAD+‐dependent enzymes which catalyze protein lysine deacylation and mono ADP‐ribosylation. Sirtuins act as central regulators of genomic stability and gene expression and control key processes, including energetic metabolism, cell cycle, differentiation, apoptosis, and aging.
Francesco Fiorentino   +3 more
wiley   +1 more source

Evidence of Influenza A in Wild Norway Rats (Rattus norvegicus) in Boston, Massachusetts

open access: yesFrontiers in Ecology and Evolution, 2019
Influenza A virus (IAV) is known to circulate among human and animal reservoirs, yet there are few studies that address the potential for urban rodents to carry and shed IAV.
Charles O. Cummings   +7 more
doaj   +1 more source

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